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A novel antibody for the detection of alternatively spliced secreted KLOTHO isoform in human plasma
αKlotho is primarily known to express as a transmembrane protein. Proteolytic cleavage results in shedding of the extracellular domain which enters systemic circulation. A truncated form of αKlotho resulting from alternative splicing of the αKLOTHO transcript exists and is believed to be secreted, t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822350/ https://www.ncbi.nlm.nih.gov/pubmed/33481901 http://dx.doi.org/10.1371/journal.pone.0245614 |