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Testicular Torsion in a Rare Case of Prostatic Spindle Cell Rhabdomyosarcoma

Spindle cell sarcoma of the prostate is a rare variant of rhabdomyosarcoma (RMS), with the clinical experience limited to a handful of cases in the literature. We report a rare case of spindle cell rhabdomyosarcoma (SC-RMS) who presented to us with testicular torsion features. A 20-year-old male pre...

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Autores principales: Ashuvanth, Subramaniyan, Sinduja, Ramanan, Vijayakumar, Chellappa, Kumbhar, Uday, Toi, Pampa C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822391/
https://www.ncbi.nlm.nih.gov/pubmed/33505810
http://dx.doi.org/10.7759/cureus.12238
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author Ashuvanth, Subramaniyan
Sinduja, Ramanan
Vijayakumar, Chellappa
Kumbhar, Uday
Toi, Pampa C
author_facet Ashuvanth, Subramaniyan
Sinduja, Ramanan
Vijayakumar, Chellappa
Kumbhar, Uday
Toi, Pampa C
author_sort Ashuvanth, Subramaniyan
collection PubMed
description Spindle cell sarcoma of the prostate is a rare variant of rhabdomyosarcoma (RMS), with the clinical experience limited to a handful of cases in the literature. We report a rare case of spindle cell rhabdomyosarcoma (SC-RMS) who presented to us with testicular torsion features. A 20-year-old male presented initially with lower urinary tract symptoms and features of epidiymo-orchitis, which was managed conservatively. He later presented with features suggestive of testicular torsion and underwent orchidopexy. The patient developed postoperative urinary retention. On per-rectal examination, there was gross prostatomegaly. He was evaluated with a trans-rectal biopsy and contrast-enhanced computed tomography (CECT). Subsequently, he was found to have metastatic prostatic SC-RMS, which is a rare disease. He was started on chemotherapy and radiotherapy. SC-RMS is a variant that has a comparatively favorable prognosis in children and an aggressive course in adults, as reported in the few cases so far. The treatment regimen is still evolving, and there is no consensus on the therapeutic approach. All these factors together result in the dismal outlook of patients diagnosed with this condition.
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spelling pubmed-78223912021-01-26 Testicular Torsion in a Rare Case of Prostatic Spindle Cell Rhabdomyosarcoma Ashuvanth, Subramaniyan Sinduja, Ramanan Vijayakumar, Chellappa Kumbhar, Uday Toi, Pampa C Cureus Pathology Spindle cell sarcoma of the prostate is a rare variant of rhabdomyosarcoma (RMS), with the clinical experience limited to a handful of cases in the literature. We report a rare case of spindle cell rhabdomyosarcoma (SC-RMS) who presented to us with testicular torsion features. A 20-year-old male presented initially with lower urinary tract symptoms and features of epidiymo-orchitis, which was managed conservatively. He later presented with features suggestive of testicular torsion and underwent orchidopexy. The patient developed postoperative urinary retention. On per-rectal examination, there was gross prostatomegaly. He was evaluated with a trans-rectal biopsy and contrast-enhanced computed tomography (CECT). Subsequently, he was found to have metastatic prostatic SC-RMS, which is a rare disease. He was started on chemotherapy and radiotherapy. SC-RMS is a variant that has a comparatively favorable prognosis in children and an aggressive course in adults, as reported in the few cases so far. The treatment regimen is still evolving, and there is no consensus on the therapeutic approach. All these factors together result in the dismal outlook of patients diagnosed with this condition. Cureus 2020-12-23 /pmc/articles/PMC7822391/ /pubmed/33505810 http://dx.doi.org/10.7759/cureus.12238 Text en Copyright © 2020, Ashuvanth et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Ashuvanth, Subramaniyan
Sinduja, Ramanan
Vijayakumar, Chellappa
Kumbhar, Uday
Toi, Pampa C
Testicular Torsion in a Rare Case of Prostatic Spindle Cell Rhabdomyosarcoma
title Testicular Torsion in a Rare Case of Prostatic Spindle Cell Rhabdomyosarcoma
title_full Testicular Torsion in a Rare Case of Prostatic Spindle Cell Rhabdomyosarcoma
title_fullStr Testicular Torsion in a Rare Case of Prostatic Spindle Cell Rhabdomyosarcoma
title_full_unstemmed Testicular Torsion in a Rare Case of Prostatic Spindle Cell Rhabdomyosarcoma
title_short Testicular Torsion in a Rare Case of Prostatic Spindle Cell Rhabdomyosarcoma
title_sort testicular torsion in a rare case of prostatic spindle cell rhabdomyosarcoma
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822391/
https://www.ncbi.nlm.nih.gov/pubmed/33505810
http://dx.doi.org/10.7759/cureus.12238
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