Cargando…

Drug Repurposing Approach against Novel Coronavirus Disease (COVID-19) through Virtual Screening Targeting SARS-CoV-2 Main Protease

SIMPLE SUMMARY: With the urgent necessity of potential treatment against novel coronavirus disease, we used several computational methods to search for active drugs from an extensive database. The results of our investigation suggested several established drugs that can be subjected to further analy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chowdhury, Kamrul Hasan, Chowdhury, Md. Riad, Mahmud, Shafi, Tareq, Abu Montakim, Hanif, Nujhat Binte, Banu, Naureen, Reza, A. S. M. Ali, Emran, Talha Bin, Simal-Gandara, Jesus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822464/ https://www.ncbi.nlm.nih.gov/pubmed/33374717 http://dx.doi.org/10.3390/biology10010002

Ejemplares similares

Insightful Valorization of the Biological Activities of Pani Heloch Leaves through Experimental and Computer-Aided Mechanisms
por: Banu, Naureen, et al.
Publicado: (2020)

An integrated exploration of pharmacological potencies of Bischofia javanica (Blume) leaves through experimental and computational modeling
por: Chowdhury, Md. Riad, et al.
Publicado: (2020)

Plant-Based Indole Alkaloids: A Comprehensive Overview from a Pharmacological Perspective
por: Omar, Faisal, et al.
Publicado: (2021)

Chemical Profiles and Pharmacological Properties with in Silico Studies on Elatostema papillosum Wedd
por: Uddin, Md. Zia, et al.
Publicado: (2021)

Ethnomedicinal Value of Antidiabetic Plants in Bangladesh: A Comprehensive Review
por: Rahman, Md. Masudur, et al.
Publicado: (2021)

Plant-Based Phytochemical Screening by Targeting Main Protease of SARS-CoV-2 to Design Effective Potent Inhibitors
por: Mahmud, Shafi, et al.
Publicado: (2021)

Phytochemicals from Leucas zeylanica Targeting Main Protease of SARS-CoV-2: Chemical Profiles, Molecular Docking, and Molecular Dynamics Simulations
por: Dutta, Mycal, et al.
Publicado: (2021)

The Genus Curcuma and Inflammation: Overview of the Pharmacological Perspectives
por: Rahaman, Md. Moshiur, et al.
Publicado: (2020)

Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective
por: Chakraborty, Arka Jyoti, et al.
Publicado: (2021)

Mucormycosis coinfection in the context of global COVID-19 outbreak: A fatal addition to the pandemic spectrum
por: Devnath, Popy, et al.
Publicado: (2021)

Beta-Arrestins in the Treatment of Heart Failure Related to Hypertension: A Comprehensive Review
por: Rakib, Ahmed, et al.
Publicado: (2021)

Impact of SARS-CoV-2 delta variant (B.1.617.2) in surging second wave of COVID-19 and efficacy of vaccines in tackling the ongoing pandemic
por: Tareq, Abu Montakim, et al.
Publicado: (2021)

Virtual screening and repurposing of FDA approved drugs against COVID-19 main protease
por: Kandeel, Mahmoud, et al.
Publicado: (2020)

Identification of repurposing therapeutics toward SARS-CoV-2 main protease by virtual screening
por: Sanachai, Kamonpan, et al.
Publicado: (2022)

Integrated computational approach towards repurposing of antimalarial drug against SARS-CoV-2 main protease
por: Gogoi, Neelutpal, et al.
Publicado: (2022)

Antiviral peptides against the main protease of SARS-CoV-2: A molecular docking and dynamics study
por: Mahmud, Shafi, et al.
Publicado: (2021)

Prospective Role of Peptide-Based Antiviral Therapy Against the Main Protease of SARS-CoV-2
por: Mahmud, Shafi, et al.
Publicado: (2021)

Deciphering the Pharmacological Properties of Methanol Extract of Psychotria calocarpa Leaves by In Vivo, In Vitro and In Silico Approaches
por: Bristy, Tahmina Akter, et al.
Publicado: (2020)

In Silico Evaluation of Iranian Medicinal Plant Phytoconstituents as Inhibitors against Main Protease and the Receptor-Binding Domain of SARS-CoV-2
por: Mousavi, Seyyed Sasan, et al.
Publicado: (2021)

Impact of Drug Repurposing on SARS-Cov-2 Main Protease
por: Ndagi, Umar, et al.
Publicado: (2023)

Antioxidant-Rich Woodfordia fruticosa Leaf Extract Alleviates Depressive-Like Behaviors and Impede Hyperglycemia
por: Tayab, Mohammed Abu, et al.
Publicado: (2021)

Terpenes and terpenoids as main bioactive compounds of essential oils, their roles in human health and potential application as natural food preservatives
por: Masyita, Ayu, et al.
Publicado: (2022)

Biochemical and Computational Approach of Selected Phytocompounds from Tinospora crispa in the Management of COVID-19
por: Rakib, Ahmed, et al.
Publicado: (2020)

Ligand and structure-based virtual screening applied to the SARS-CoV-2 main protease: an in silico repurposing study
por: Ferraz, Witor Ribeiro, et al.
Publicado: (2020)

Screening of Potent Phytochemical Inhibitors Against SARS-CoV-2 Main Protease: An Integrative Computational Approach
por: Mahmud, Shafi, et al.
Publicado: (2021)

Biological Evaluation, DFT Calculations and Molecular Docking Studies on the Antidepressant and Cytotoxicity Activities of Cycas pectinata Buch.-Ham. Compounds
por: Rahman, Jinnat, et al.
Publicado: (2020)

Current State and Promising Opportunities on Pharmaceutical Approaches in the Treatment of Polymicrobial Diseases
por: Sartini, Sartini, et al.
Publicado: (2021)

Unveiling pharmacological studies provide new insights on Mangifera longipes and Quercus gomeziana
por: Guha, Bishwajit, et al.
Publicado: (2021)

Repurposing metocurine as main protease inhibitor to develop novel antiviral therapy for COVID-19
por: Jain, Rashi, et al.
Publicado: (2020)

Anti-Inflammatory, Thrombolytic and Hair-Growth Promoting Activity of the n-Hexane Fraction of the Methanol Extract of Leea indica Leaves
por: Sakib, Shahenur Alam, et al.
Publicado: (2021)

Chemical Profiling, Pharmacological Insights and In Silico Studies of Methanol Seed Extract of Sterculia foetida
por: Alam, Najmul, et al.
Publicado: (2021)

Targeting SARS-CoV-2 Main Protease: A Computational Drug Repurposing Study
por: Baby, Krishnaprasad, et al.
Publicado: (2021)

Drug Repurposing and Polypharmacology to Fight SARS-CoV-2 Through Inhibition of the Main Protease
por: Pinzi, Luca, et al.
Publicado: (2021)

Thermodynamic and structural insights into the repurposing of drugs that bind to SARS-CoV-2 main protease
por: Wan, Shunzhou, et al.
Publicado: (2021)

Repurposing Halicin as a potent covalent inhibitor for the SARS-CoV-2 main protease
por: Yang, Kai S., et al.
Publicado: (2022)

Repurposing of renin inhibitors as SARS-COV-2 main protease inhibitors: A computational study
por: Refaey, Rana H., et al.
Publicado: (2021)

SARS-CoV-2 main protease targeting potent fluorescent inhibitors: Repurposing thioxanthones
por: BATIBAY, Gönül S., et al.
Publicado: (2023)

In vivo and in vitro evaluation of pharmacological activities of Adenia trilobata (Roxb.)
por: Barua, Niloy, et al.
Publicado: (2020)

High-throughput screening and evaluation of repurposed drugs targeting the SARS-CoV-2 main protease
por: Li, Yan, et al.
Publicado: (2021)

Drug repurposing for SARS-CoV-2 main protease: Molecular docking and molecular dynamics investigations
por: Omer, Samia E., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_boibqodrt9ob93akobh7b4mksq