The potential of microdialysis to estimate rifampicin concentrations in the lung of guinea pigs

Optimised pre-clinical models are required for TB drug development to better predict the pharmacokinetics of anti-tuberculosis (anti-TB) drugs to shorten the time taken for novel drugs and combinations to be approved for clinical trial. Microdialysis can be used to measure unbound drug concentration...

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Detalles Bibliográficos
Autores principales: Lanni, Faye, Burton, Neil, Harris, Debbie, Fotheringham, Susan, Clark, Simon, Skinner, Oliver, Wiblin, Nathan, Dennis, Mike, Armstrong, Stuart, Davies, Geraint, Williams, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822530/
https://www.ncbi.nlm.nih.gov/pubmed/33481939
http://dx.doi.org/10.1371/journal.pone.0245922

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