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Differential role of cytosolic Hsp70s in longevity assurance and protein quality control

70 kDa heat shock proteins (Hsp70) are essential chaperones of the protein quality control network; vital for cellular fitness and longevity. The four cytosolic Hsp70’s in yeast, Ssa1-4, are thought to be functionally redundant but the absence of Ssa1 and Ssa2 causes a severe reduction in cellular r...

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Detalles Bibliográficos
Autores principales: Andersson, Rebecca, Eisele-Bürger, Anna Maria, Hanzén, Sarah, Vielfort, Katarina, Öling, David, Eisele, Frederik, Johansson, Gustav, Gustafsson, Tobias, Kvint, Kristian, Nyström, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822560/
https://www.ncbi.nlm.nih.gov/pubmed/33428620
http://dx.doi.org/10.1371/journal.pgen.1008951