Tofacitinib Ameliorates Lipopolysaccharide-Induced Acute Kidney Injury by Blocking the JAK-STAT1/STAT3 Signaling Pathway

Septic acute kidney injury (AKI) is the most common AKI syndrome in the intensive care unit (ICU), and it accounts for approximately half of AKI cases. Tofacitinib (TOFA) is a pan-Janus kinase (JAK) inhibitor that exhibits potent anti-inflammatory activity in rheumatoid arthritis. However, no study...

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Detalles Bibliográficos
Autores principales: Yun, Yang, Chen, Jingyu, Wang, Xuejiao, Li, Yingzhuo, Hu, Zhifan, Yang, Pingting, Qin, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822662/
https://www.ncbi.nlm.nih.gov/pubmed/33511217
http://dx.doi.org/10.1155/2021/8877056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822662/
https://www.ncbi.nlm.nih.gov/pubmed/33511217
http://dx.doi.org/10.1155/2021/8877056

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