W196 and the β-Hairpin Motif Modulate the Redox Switch of Conformation and the Biomolecular Interaction Network of the Apoptosis-Inducing Factor

The human apoptosis-inducing factor (hAIF) is a moonlight flavoprotein involved in mitochondrial respiratory complex assembly and caspase-independent programmed cell death. These functions might be modulated by its redox-linked structural transition that enables hAIF to act as a NAD(H/(+)) redox sen...

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Detalles Bibliográficos
Autores principales: Romero-Tamayo, Silvia, Laplaza, Ruben, Velazquez-Campoy, Adrian, Villanueva, Raquel, Medina, Milagros, Ferreira, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822688/
https://www.ncbi.nlm.nih.gov/pubmed/33510840
http://dx.doi.org/10.1155/2021/6673661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822688/
https://www.ncbi.nlm.nih.gov/pubmed/33510840
http://dx.doi.org/10.1155/2021/6673661

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