The mutation profile of differentiated thyroid cancer coexisting with undifferentiated anaplastic cancer resembles that of anaplastic thyroid cancer but not that of archetypal differentiated thyroid cancer

Differentiated thyroid cancer (DTC) has one of the lowest cancer mutational burdens, while anaplastic thyroid cancer (ATC) has a much higher mutation frequency. A fraction of ATC has an associated differentiated component, which suggests the coevolution of both cancers. Here, we aimed to compare mut...

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Detalles Bibliográficos
Autores principales: Mika, Justyna, Łabaj, Wojciech, Chekan, Mykola, Abramowicz, Agata, Pietrowska, Monika, Polański, Andrzej, Widłak, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Human Genetics • Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822790/
https://www.ncbi.nlm.nih.gov/pubmed/33222100
http://dx.doi.org/10.1007/s13353-020-00594-0

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