SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques

CD4 T follicular helper (T(fh)) cells are important for the generation of durable and specific humoral protection against viral infections. The degree to which SARS-CoV-2 infection generates T(fh) cells and stimulates the germinal center (GC) response is an important question as we investigate vacci...

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Autores principales: Shaan Lakshmanappa, Yashavanth, Elizaldi, Sonny R., Roh, Jamin W., Schmidt, Brian A., Carroll, Timothy D., Weaver, Kourtney D., Smith, Justin C., Verma, Anil, Deere, Jesse D., Dutra, Joseph, Stone, Mars, Franz, Sergej, Sammak, Rebecca Lee, Olstad, Katherine J., Rachel Reader, J., Ma, Zhong-Min, Nguyen, Nancy K., Watanabe, Jennifer, Usachenko, Jodie, Immareddy, Ramya, Yee, JoAnn L., Weiskopf, Daniela, Sette, Alessandro, Hartigan-O’Connor, Dennis, McSorley, Stephen J., Morrison, John H., Tran, Nam K., Simmons, Graham, Busch, Michael P., Kozlowski, Pamela A., Van Rompay, Koen K. A., Miller, Christopher J., Iyer, Smita S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822826/
https://www.ncbi.nlm.nih.gov/pubmed/33483492
http://dx.doi.org/10.1038/s41467-020-20642-x

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