Mild synthesis of isoxazoline derivatives via an efficient [4 + 1] annulation reaction of transient nitrosoalkenes and sulfur ylides

An efficient [4 + 1] annulation between α-bromooximes and sulfur ylides via in situ generation of nitrosoalkenes under mild basic reaction conditions has been developed, providing an expeditious and scalable approach to synthesize biologically interesting isoxazoline derivatives with good to excelle...

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Detalles Bibliográficos
Autores principales: Hua, Ting-Bi, Liu, Cheng-Xiong, Hu, Wei-Min, Wang, Long, Yang, Qing-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822858/
https://www.ncbi.nlm.nih.gov/pubmed/33483530
http://dx.doi.org/10.1038/s41598-021-81370-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822858/
https://www.ncbi.nlm.nih.gov/pubmed/33483530
http://dx.doi.org/10.1038/s41598-021-81370-w

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