Sept8/SEPTIN8 involvement in cellular structure and kidney damage is identified by genetic mapping and a novel human tubule hypoxic model

Chronic kidney disease (CKD), which can ultimately progress to kidney failure, is influenced by genetics and the environment. Genes identified in human genome wide association studies (GWAS) explain only a small proportion of the heritable variation and lack functional validation, indicating the nee...

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Detalles Bibliográficos
Autores principales: Keele, Gregory R., Prokop, Jeremy W., He, Hong, Holl, Katie, Littrell, John, Deal, Aaron W., Kim, Yunjung, Kyle, Patrick B., Attipoe, Esinam, Johnson, Ashley C., Uhl, Katie L., Sirpilla, Olivia L., Jahanbakhsh, Seyedehameneh, Robinson, Melanie, Levy, Shawn, Valdar, William, Garrett, Michael R., Solberg Woods, Leah C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822875/
https://www.ncbi.nlm.nih.gov/pubmed/33483609
http://dx.doi.org/10.1038/s41598-021-81550-8

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