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Structural basis of ribosomal RNA transcription regulation

Ribosomal RNA (rRNA) is most highly expressed in rapidly growing bacteria and is drastically downregulated under stress conditions by the global transcriptional regulator DksA and the alarmone ppGpp. Here, we determined cryo-electron microscopy structures of the Escherichia coli RNA polymerase (RNAP...

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Detalles Bibliográficos
Autores principales:	Shin, Yeonoh, Qayyum, M. Zuhaib, Pupov, Danil, Esyunina, Daria, Kulbachinskiy, Andrey, Murakami, Katsuhiko S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822876/ https://www.ncbi.nlm.nih.gov/pubmed/33483500 http://dx.doi.org/10.1038/s41467-020-20776-y

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