Loss of Parkinson’s susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis

Pathological links between neurodegenerative disease and cancer are emerging. LRRK2 overactivity contributes to Parkinson’s disease, whereas our previous analyses of public cancer patient data revealed that decreased LRRK2 expression is associated with lung adenocarcinoma (LUAD). The clinical and fu...

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Detalles Bibliográficos
Autores principales: Lebovitz, Chandra, Wretham, Nicole, Osooly, Maryam, Milne, Katy, Dash, Tia, Thornton, Shelby, Tessier-Cloutier, Basile, Sathiyaseelan, Paalini, Bortnik, Svetlana, Go, Nancy Erro, Halvorsen, Elizabeth, Cederberg, Rachel A., Chow, Norman, Dos Santos, Nancy, Bennewith, Kevin L., Nelson, Brad H., Bally, Marcel B., Lam, Wan L., Gorski, Sharon M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822882/
https://www.ncbi.nlm.nih.gov/pubmed/33483550
http://dx.doi.org/10.1038/s41598-021-81639-0

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