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Genetic deletion of Abcc6 disturbs cholesterol homeostasis in mice

Genetic studies link adenosine triphosphate-binding cassette transporter C6 (ABCC6) mutations to pseudoxanthoma elasticum (PXE). ABCC6 sequence variations are correlated with altered HDL cholesterol levels and an elevated risk of coronary artery diseases. However, the role of ABCC6 in cholesterol ho...

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Detalles Bibliográficos
Autores principales:	Ibold, Bettina, Tiemann, Janina, Faust, Isabel, Ceglarek, Uta, Dittrich, Julia, Gorgels, Theo G. M. F., Bergen, Arthur A. B., Vanakker, Olivier, Van Gils, Matthias, Knabbe, Cornelius, Hendig, Doris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822913/ https://www.ncbi.nlm.nih.gov/pubmed/33483533 http://dx.doi.org/10.1038/s41598-021-81573-1

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