RNA editing enzyme APOBEC3A promotes pro-inflammatory M1 macrophage polarization

Pro-inflammatory M1 macrophage polarization is associated with microbicidal and antitumor responses. We recently described APOBEC3A-mediated cytosine-to-uracil (C > U) RNA editing during M1 polarization. However, the functional significance of this editing is unknown. Here we find that APOBEC3A-m...

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Detalles Bibliográficos
Autores principales: Alqassim, Emad Y., Sharma, Shraddha, Khan, A. N. M. Nazmul H., Emmons, Tiffany R., Cortes Gomez, Eduardo, Alahmari, Abdulrahman, Singel, Kelly L., Mark, Jaron, Davidson, Bruce A., Robert McGray, A. J., Liu, Qian, Lichty, Brian D., Moysich, Kirsten B., Wang, Jianmin, Odunsi, Kunle, Segal, Brahm H., Baysal, Bora E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822933/
https://www.ncbi.nlm.nih.gov/pubmed/33483601
http://dx.doi.org/10.1038/s42003-020-01620-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822933/
https://www.ncbi.nlm.nih.gov/pubmed/33483601
http://dx.doi.org/10.1038/s42003-020-01620-x

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