Cargando…

Zfp521 is essential for the quiescence and maintenance of adult hematopoietic stem cells under stress

Zinc finger protein 521 (Zfp521), a quiescent hematopoietic stem cell (HSC)-enriched transcription factor, is involved in the self-renewal and differentiation of fetal liver HSC. However, its role in adult hematopoiesis remains elusive. Here, we found that Zfp521 deletion did not inhibit adult hemat...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Zhigang, Fu, Xuemei, Wu, Weiru, Liu, Zhilong, Chen, Zhe, Zhou, Chengfang, Liu, Yuanyuan, Kuang, Mei, Sun, Fangfang, Xiao, Feifei, Huang, Yongxiu, Zhang, Xiaojun, Fan, Shijun, Huang, Xingqin, Zheng, Guangling, Chen, Jieping, Hou, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822949/
https://www.ncbi.nlm.nih.gov/pubmed/33532716
http://dx.doi.org/10.1016/j.isci.2021.102039