Zfp521 is essential for the quiescence and maintenance of adult hematopoietic stem cells under stress

Zinc finger protein 521 (Zfp521), a quiescent hematopoietic stem cell (HSC)-enriched transcription factor, is involved in the self-renewal and differentiation of fetal liver HSC. However, its role in adult hematopoiesis remains elusive. Here, we found that Zfp521 deletion did not inhibit adult hemat...

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Detalles Bibliográficos
Autores principales: Li, Zhigang, Fu, Xuemei, Wu, Weiru, Liu, Zhilong, Chen, Zhe, Zhou, Chengfang, Liu, Yuanyuan, Kuang, Mei, Sun, Fangfang, Xiao, Feifei, Huang, Yongxiu, Zhang, Xiaojun, Fan, Shijun, Huang, Xingqin, Zheng, Guangling, Chen, Jieping, Hou, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7822949/
https://www.ncbi.nlm.nih.gov/pubmed/33532716
http://dx.doi.org/10.1016/j.isci.2021.102039

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