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Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note
Articular cartilage lesions are identified with increasing frequency. Several cartilage repair techniques are available to treat symptomatic cartilage defects. The ultimate goal of any cartilage repair procedure is the prevention of premature osteoarthritis. Autologous chondrocyte implantation provi...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823081/ https://www.ncbi.nlm.nih.gov/pubmed/33532215 http://dx.doi.org/10.1016/j.eats.2020.09.015 |
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author | Schneider, Stefan Ossendorff, Robert Holz, Johannes Salzmann, Gian M. |
author_facet | Schneider, Stefan Ossendorff, Robert Holz, Johannes Salzmann, Gian M. |
author_sort | Schneider, Stefan |
collection | PubMed |
description | Articular cartilage lesions are identified with increasing frequency. Several cartilage repair techniques are available to treat symptomatic cartilage defects. The ultimate goal of any cartilage repair procedure is the prevention of premature osteoarthritis. Autologous chondrocyte implantation provides the best tissue quality. However, 2 operations and a resource-intense culturing process with high regulatory demands are disadvantages of this cartilage repair procedure. Furthermore, cellular dedifferentiation and senescence display further cell culture-associated drawbacks that hamper the procedure. Minced cartilage implantation is a relatively simple and cost-effective one-step procedure with promising biologic potential and satisfying clinical results. We present an arthroscopic surgical technique where the surgeon can apply autologous chondrocytes in a one-step procedure to treat articular cartilage defects at the knee joint. |
format | Online Article Text |
id | pubmed-7823081 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-78230812021-02-01 Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note Schneider, Stefan Ossendorff, Robert Holz, Johannes Salzmann, Gian M. Arthrosc Tech Technical Note Articular cartilage lesions are identified with increasing frequency. Several cartilage repair techniques are available to treat symptomatic cartilage defects. The ultimate goal of any cartilage repair procedure is the prevention of premature osteoarthritis. Autologous chondrocyte implantation provides the best tissue quality. However, 2 operations and a resource-intense culturing process with high regulatory demands are disadvantages of this cartilage repair procedure. Furthermore, cellular dedifferentiation and senescence display further cell culture-associated drawbacks that hamper the procedure. Minced cartilage implantation is a relatively simple and cost-effective one-step procedure with promising biologic potential and satisfying clinical results. We present an arthroscopic surgical technique where the surgeon can apply autologous chondrocytes in a one-step procedure to treat articular cartilage defects at the knee joint. Elsevier 2020-12-19 /pmc/articles/PMC7823081/ /pubmed/33532215 http://dx.doi.org/10.1016/j.eats.2020.09.015 Text en © 2020 by the Arthroscopy Association of North America. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Technical Note Schneider, Stefan Ossendorff, Robert Holz, Johannes Salzmann, Gian M. Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note |
title | Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note |
title_full | Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note |
title_fullStr | Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note |
title_full_unstemmed | Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note |
title_short | Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note |
title_sort | arthroscopic minced cartilage implantation (mci): a technical note |
topic | Technical Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823081/ https://www.ncbi.nlm.nih.gov/pubmed/33532215 http://dx.doi.org/10.1016/j.eats.2020.09.015 |
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