Cargando…

Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note

Articular cartilage lesions are identified with increasing frequency. Several cartilage repair techniques are available to treat symptomatic cartilage defects. The ultimate goal of any cartilage repair procedure is the prevention of premature osteoarthritis. Autologous chondrocyte implantation provi...

Descripción completa

Detalles Bibliográficos
Autores principales: Schneider, Stefan, Ossendorff, Robert, Holz, Johannes, Salzmann, Gian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823081/
https://www.ncbi.nlm.nih.gov/pubmed/33532215
http://dx.doi.org/10.1016/j.eats.2020.09.015
_version_ 1783639758111506432
author Schneider, Stefan
Ossendorff, Robert
Holz, Johannes
Salzmann, Gian M.
author_facet Schneider, Stefan
Ossendorff, Robert
Holz, Johannes
Salzmann, Gian M.
author_sort Schneider, Stefan
collection PubMed
description Articular cartilage lesions are identified with increasing frequency. Several cartilage repair techniques are available to treat symptomatic cartilage defects. The ultimate goal of any cartilage repair procedure is the prevention of premature osteoarthritis. Autologous chondrocyte implantation provides the best tissue quality. However, 2 operations and a resource-intense culturing process with high regulatory demands are disadvantages of this cartilage repair procedure. Furthermore, cellular dedifferentiation and senescence display further cell culture-associated drawbacks that hamper the procedure. Minced cartilage implantation is a relatively simple and cost-effective one-step procedure with promising biologic potential and satisfying clinical results. We present an arthroscopic surgical technique where the surgeon can apply autologous chondrocytes in a one-step procedure to treat articular cartilage defects at the knee joint.
format Online
Article
Text
id pubmed-7823081
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-78230812021-02-01 Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note Schneider, Stefan Ossendorff, Robert Holz, Johannes Salzmann, Gian M. Arthrosc Tech Technical Note Articular cartilage lesions are identified with increasing frequency. Several cartilage repair techniques are available to treat symptomatic cartilage defects. The ultimate goal of any cartilage repair procedure is the prevention of premature osteoarthritis. Autologous chondrocyte implantation provides the best tissue quality. However, 2 operations and a resource-intense culturing process with high regulatory demands are disadvantages of this cartilage repair procedure. Furthermore, cellular dedifferentiation and senescence display further cell culture-associated drawbacks that hamper the procedure. Minced cartilage implantation is a relatively simple and cost-effective one-step procedure with promising biologic potential and satisfying clinical results. We present an arthroscopic surgical technique where the surgeon can apply autologous chondrocytes in a one-step procedure to treat articular cartilage defects at the knee joint. Elsevier 2020-12-19 /pmc/articles/PMC7823081/ /pubmed/33532215 http://dx.doi.org/10.1016/j.eats.2020.09.015 Text en © 2020 by the Arthroscopy Association of North America. Published by Elsevier. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Technical Note
Schneider, Stefan
Ossendorff, Robert
Holz, Johannes
Salzmann, Gian M.
Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note
title Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note
title_full Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note
title_fullStr Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note
title_full_unstemmed Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note
title_short Arthroscopic Minced Cartilage Implantation (MCI): A Technical Note
title_sort arthroscopic minced cartilage implantation (mci): a technical note
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823081/
https://www.ncbi.nlm.nih.gov/pubmed/33532215
http://dx.doi.org/10.1016/j.eats.2020.09.015
work_keys_str_mv AT schneiderstefan arthroscopicmincedcartilageimplantationmciatechnicalnote
AT ossendorffrobert arthroscopicmincedcartilageimplantationmciatechnicalnote
AT holzjohannes arthroscopicmincedcartilageimplantationmciatechnicalnote
AT salzmanngianm arthroscopicmincedcartilageimplantationmciatechnicalnote