Effect of an alkyl spacer on the morphology and internalization of MUC1 aptamer‐naphthalimide amphiphiles for targeting and imaging triple negative breast cancer cells

Despite decades of research, there are few targeted treatment options available for triple negative breast cancer (TNBC), leaving chemotherapy, and radiation treatment regimes with poor response and high toxicity. Herein aptamer‐amphiphiles were synthesized which selectively bind to the mucin‐1 (MUC...

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Detalles Bibliográficos
Autores principales: Kuang, Huihui, Schneiderman, Zachary, Shabana, Ahmed M., Russo, Gabriella C., Guo, Jun, Wirtz, Denis, Kokkoli, Efrosini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823120/
https://www.ncbi.nlm.nih.gov/pubmed/33532593
http://dx.doi.org/10.1002/btm2.10194

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