ROCK2 Promotes Osteosarcoma Growth and Glycolysis by Up-Regulating HKII via Phospho-PI3K/AKT Signalling

BACKGROUND: Osteosarcoma (OS) is a malignant bone tumour that exhibits a high mortality. While tumours thrive in a state of malnutrition, the mechanism by which OS cells adapt to metabolic stress through metabolic reprogramming remains unclear. METHODS: We analysed the expression of ROCK2 in osteosa...

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Detalles Bibliográficos
Autores principales: Deng, Binbin, Deng, Jianyong, Yi, Xuan, Zou, Yeqing, Li, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823140/
https://www.ncbi.nlm.nih.gov/pubmed/33500659
http://dx.doi.org/10.2147/CMAR.S279496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823140/
https://www.ncbi.nlm.nih.gov/pubmed/33500659
http://dx.doi.org/10.2147/CMAR.S279496

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