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ROCK2 Promotes Osteosarcoma Growth and Glycolysis by Up-Regulating HKII via Phospho-PI3K/AKT Signalling
BACKGROUND: Osteosarcoma (OS) is a malignant bone tumour that exhibits a high mortality. While tumours thrive in a state of malnutrition, the mechanism by which OS cells adapt to metabolic stress through metabolic reprogramming remains unclear. METHODS: We analysed the expression of ROCK2 in osteosa...
Autores principales: | Deng, Binbin, Deng, Jianyong, Yi, Xuan, Zou, Yeqing, Li, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823140/ https://www.ncbi.nlm.nih.gov/pubmed/33500659 http://dx.doi.org/10.2147/CMAR.S279496 |
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