Galanin promotes autophagy and alleviates apoptosis in the hypertrophied heart through FoxO1 pathway

Autophagy and apoptosis are powerful regulators of multiple facets of cellular metabolism and homeostasis. Here, we uncover that galanin, a pleiotropic peptide, regulates cardiac autophagy and deactivates apoptotic cell death through the Forkhead box protein O1 (FoxO1) pathway. In hypertrophied hear...

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Detalles Bibliográficos
Autores principales: Martinelli, Ilenia, Timotin, Andrei, Moreno-Corchado, Paula, Marsal, Dimitri, Kramar, Solomiia, Loy, Halina, Joffre, Carine, Boal, Frederic, Tronchere, Helene, Kunduzova, Oksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823211/
https://www.ncbi.nlm.nih.gov/pubmed/33493902
http://dx.doi.org/10.1016/j.redox.2021.101866

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