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Kidney Transplantation and Diagnostic Imaging: The Early Days and Future Advancements of Transplant Surgery

The first steps for modern organ transplantation were taken by Emerich Ullmann (Vienne, Austria) in 1902, with a dog-to-dog kidney transplant, and ultimate success was achieved by Joseph Murray in 1954, with the Boston twin brothers. In the same time period, the ground-breaking work of Wilhelm C. Rö...

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Autores principales: Benjamens, Stan, Moers, Cyril, Slart, Riemer H.J.A., Pol, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823312/
https://www.ncbi.nlm.nih.gov/pubmed/33396860
http://dx.doi.org/10.3390/diagnostics11010047
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author Benjamens, Stan
Moers, Cyril
Slart, Riemer H.J.A.
Pol, Robert A.
author_facet Benjamens, Stan
Moers, Cyril
Slart, Riemer H.J.A.
Pol, Robert A.
author_sort Benjamens, Stan
collection PubMed
description The first steps for modern organ transplantation were taken by Emerich Ullmann (Vienne, Austria) in 1902, with a dog-to-dog kidney transplant, and ultimate success was achieved by Joseph Murray in 1954, with the Boston twin brothers. In the same time period, the ground-breaking work of Wilhelm C. Röntgen (1895) and Maria Sklodowska-Curie (1903), on X-rays and radioactivity, enabled the introduction of diagnostic imaging. In the years thereafter, kidney transplantation and diagnostic imaging followed a synergistic path for their development, with key discoveries in transplant rejection pathways, immunosuppressive therapies, and the integration of diagnostic imaging in transplant programs. The first image of a transplanted kidney, a urogram with intravenous contrast, was shown to the public in 1956, and the first recommendations for transplantation diagnostic imaging were published in 1958. Transplant surgeons were eager to use innovative diagnostic modalities, with renal scintigraphy in the 1960s, as well as ultrasound and computed tomography in the 1970s. The use of innovative diagnostic modalities has had a great impact on the reduction of post-operative complications in kidney transplantation, making it one of the key factors for successful transplantation. For the new generation of transplant surgeons, the historical alignment between transplant surgery and diagnostic imaging can be a motivator for future innovations.
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spelling pubmed-78233122021-01-24 Kidney Transplantation and Diagnostic Imaging: The Early Days and Future Advancements of Transplant Surgery Benjamens, Stan Moers, Cyril Slart, Riemer H.J.A. Pol, Robert A. Diagnostics (Basel) Review The first steps for modern organ transplantation were taken by Emerich Ullmann (Vienne, Austria) in 1902, with a dog-to-dog kidney transplant, and ultimate success was achieved by Joseph Murray in 1954, with the Boston twin brothers. In the same time period, the ground-breaking work of Wilhelm C. Röntgen (1895) and Maria Sklodowska-Curie (1903), on X-rays and radioactivity, enabled the introduction of diagnostic imaging. In the years thereafter, kidney transplantation and diagnostic imaging followed a synergistic path for their development, with key discoveries in transplant rejection pathways, immunosuppressive therapies, and the integration of diagnostic imaging in transplant programs. The first image of a transplanted kidney, a urogram with intravenous contrast, was shown to the public in 1956, and the first recommendations for transplantation diagnostic imaging were published in 1958. Transplant surgeons were eager to use innovative diagnostic modalities, with renal scintigraphy in the 1960s, as well as ultrasound and computed tomography in the 1970s. The use of innovative diagnostic modalities has had a great impact on the reduction of post-operative complications in kidney transplantation, making it one of the key factors for successful transplantation. For the new generation of transplant surgeons, the historical alignment between transplant surgery and diagnostic imaging can be a motivator for future innovations. MDPI 2020-12-30 /pmc/articles/PMC7823312/ /pubmed/33396860 http://dx.doi.org/10.3390/diagnostics11010047 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Benjamens, Stan
Moers, Cyril
Slart, Riemer H.J.A.
Pol, Robert A.
Kidney Transplantation and Diagnostic Imaging: The Early Days and Future Advancements of Transplant Surgery
title Kidney Transplantation and Diagnostic Imaging: The Early Days and Future Advancements of Transplant Surgery
title_full Kidney Transplantation and Diagnostic Imaging: The Early Days and Future Advancements of Transplant Surgery
title_fullStr Kidney Transplantation and Diagnostic Imaging: The Early Days and Future Advancements of Transplant Surgery
title_full_unstemmed Kidney Transplantation and Diagnostic Imaging: The Early Days and Future Advancements of Transplant Surgery
title_short Kidney Transplantation and Diagnostic Imaging: The Early Days and Future Advancements of Transplant Surgery
title_sort kidney transplantation and diagnostic imaging: the early days and future advancements of transplant surgery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823312/
https://www.ncbi.nlm.nih.gov/pubmed/33396860
http://dx.doi.org/10.3390/diagnostics11010047
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