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SARS-CoV-2 Nucleocapsid Protein Interacts with RIG-I and Represses RIG-Mediated IFN-β Production

SARS-CoV-2 is highly pathogenic in humans and poses a great threat to public health worldwide. Clinical data shows a disturbed type I interferon (IFN) response during the virus infection. In this study, we discovered that the nucleocapsid (N) protein of SARS-CoV-2 plays an important role in the inhi...

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Detalles Bibliográficos
Autores principales: Chen, Keli, Xiao, Feng, Hu, Dingwen, Ge, Weiwei, Tian, Mingfu, Wang, Wenbiao, Pan, Pan, Wu, Kailang, Wu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823417/
https://www.ncbi.nlm.nih.gov/pubmed/33396605
http://dx.doi.org/10.3390/v13010047

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