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Convection-Enhanced Delivery of a First-in-Class Anti-β1 Integrin Antibody for the Treatment of High-Grade Glioma Utilizing Real-Time Imaging

Introduction: OS2966 is a first-in-class, humanized and de-immunized monoclonal antibody which targets the adhesion receptor subunit, CD29/β1 integrin. CD29 expression is highly upregulated in glioblastoma and has been shown to drive tumor progression, invasion, and resistance to multiple modalities...

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Detalles Bibliográficos
Autores principales:	Nwagwu, Chibueze D., Immidisetti, Amanda V., Bukanowska, Gabriela, Vogelbaum, Michael A., Carbonell, Anne-Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823464/ https://www.ncbi.nlm.nih.gov/pubmed/33396712 http://dx.doi.org/10.3390/pharmaceutics13010040

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