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Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review

Solitary fibrous tumors (SFTs) are mesenchymal, fibroblastic tumors with mostly favorable, but still unpredictable prognosis. Their rarity and occurrence at a variety of locations coupled with variable histological appearance make the diagnosis a challenge. This can be resolved by histological and i...

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Autores principales: Ciochon, Urszula Maria, Schmidt, Grethe, Jensen, Ruben Juhl, Loya, Anand C., Lönn, Lars Birger, Shekhrajka, Nitesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823591/
https://www.ncbi.nlm.nih.gov/pubmed/33401743
http://dx.doi.org/10.3390/diagnostics11010062
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author Ciochon, Urszula Maria
Schmidt, Grethe
Jensen, Ruben Juhl
Loya, Anand C.
Lönn, Lars Birger
Shekhrajka, Nitesh
author_facet Ciochon, Urszula Maria
Schmidt, Grethe
Jensen, Ruben Juhl
Loya, Anand C.
Lönn, Lars Birger
Shekhrajka, Nitesh
author_sort Ciochon, Urszula Maria
collection PubMed
description Solitary fibrous tumors (SFTs) are mesenchymal, fibroblastic tumors with mostly favorable, but still unpredictable prognosis. Their rarity and occurrence at a variety of locations coupled with variable histological appearance make the diagnosis a challenge. This can be resolved by histological and immunohistochemical analysis on the histologic material eventually coupled with demonstration of NAB2-STAT6 gene fusion by next generation sequencing (NGS) analysis. Tumor removal with clear surgical margins is sufficient for complete cure in most cases. Percutaneous transcatheter embolization in well-vascularized lesions may minimize the risk of bleeding during subsequent removal. In this article we present a rare case of SFT arising from the external auditory canal and treated with preoperative endovascular arterial embolization. A literature review with focus on diagnostics and treatment of this entity in the head and neck region is following.
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spelling pubmed-78235912021-01-24 Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review Ciochon, Urszula Maria Schmidt, Grethe Jensen, Ruben Juhl Loya, Anand C. Lönn, Lars Birger Shekhrajka, Nitesh Diagnostics (Basel) Case Report Solitary fibrous tumors (SFTs) are mesenchymal, fibroblastic tumors with mostly favorable, but still unpredictable prognosis. Their rarity and occurrence at a variety of locations coupled with variable histological appearance make the diagnosis a challenge. This can be resolved by histological and immunohistochemical analysis on the histologic material eventually coupled with demonstration of NAB2-STAT6 gene fusion by next generation sequencing (NGS) analysis. Tumor removal with clear surgical margins is sufficient for complete cure in most cases. Percutaneous transcatheter embolization in well-vascularized lesions may minimize the risk of bleeding during subsequent removal. In this article we present a rare case of SFT arising from the external auditory canal and treated with preoperative endovascular arterial embolization. A literature review with focus on diagnostics and treatment of this entity in the head and neck region is following. MDPI 2021-01-02 /pmc/articles/PMC7823591/ /pubmed/33401743 http://dx.doi.org/10.3390/diagnostics11010062 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Ciochon, Urszula Maria
Schmidt, Grethe
Jensen, Ruben Juhl
Loya, Anand C.
Lönn, Lars Birger
Shekhrajka, Nitesh
Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review
title Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review
title_full Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review
title_fullStr Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review
title_full_unstemmed Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review
title_short Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review
title_sort preoperative embolization of a solitary fibrous tumor originating from external auditory meatus: a case report with literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823591/
https://www.ncbi.nlm.nih.gov/pubmed/33401743
http://dx.doi.org/10.3390/diagnostics11010062
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