Cargando…
Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review
Solitary fibrous tumors (SFTs) are mesenchymal, fibroblastic tumors with mostly favorable, but still unpredictable prognosis. Their rarity and occurrence at a variety of locations coupled with variable histological appearance make the diagnosis a challenge. This can be resolved by histological and i...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823591/ https://www.ncbi.nlm.nih.gov/pubmed/33401743 http://dx.doi.org/10.3390/diagnostics11010062 |
_version_ | 1783639872049774592 |
---|---|
author | Ciochon, Urszula Maria Schmidt, Grethe Jensen, Ruben Juhl Loya, Anand C. Lönn, Lars Birger Shekhrajka, Nitesh |
author_facet | Ciochon, Urszula Maria Schmidt, Grethe Jensen, Ruben Juhl Loya, Anand C. Lönn, Lars Birger Shekhrajka, Nitesh |
author_sort | Ciochon, Urszula Maria |
collection | PubMed |
description | Solitary fibrous tumors (SFTs) are mesenchymal, fibroblastic tumors with mostly favorable, but still unpredictable prognosis. Their rarity and occurrence at a variety of locations coupled with variable histological appearance make the diagnosis a challenge. This can be resolved by histological and immunohistochemical analysis on the histologic material eventually coupled with demonstration of NAB2-STAT6 gene fusion by next generation sequencing (NGS) analysis. Tumor removal with clear surgical margins is sufficient for complete cure in most cases. Percutaneous transcatheter embolization in well-vascularized lesions may minimize the risk of bleeding during subsequent removal. In this article we present a rare case of SFT arising from the external auditory canal and treated with preoperative endovascular arterial embolization. A literature review with focus on diagnostics and treatment of this entity in the head and neck region is following. |
format | Online Article Text |
id | pubmed-7823591 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-78235912021-01-24 Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review Ciochon, Urszula Maria Schmidt, Grethe Jensen, Ruben Juhl Loya, Anand C. Lönn, Lars Birger Shekhrajka, Nitesh Diagnostics (Basel) Case Report Solitary fibrous tumors (SFTs) are mesenchymal, fibroblastic tumors with mostly favorable, but still unpredictable prognosis. Their rarity and occurrence at a variety of locations coupled with variable histological appearance make the diagnosis a challenge. This can be resolved by histological and immunohistochemical analysis on the histologic material eventually coupled with demonstration of NAB2-STAT6 gene fusion by next generation sequencing (NGS) analysis. Tumor removal with clear surgical margins is sufficient for complete cure in most cases. Percutaneous transcatheter embolization in well-vascularized lesions may minimize the risk of bleeding during subsequent removal. In this article we present a rare case of SFT arising from the external auditory canal and treated with preoperative endovascular arterial embolization. A literature review with focus on diagnostics and treatment of this entity in the head and neck region is following. MDPI 2021-01-02 /pmc/articles/PMC7823591/ /pubmed/33401743 http://dx.doi.org/10.3390/diagnostics11010062 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Ciochon, Urszula Maria Schmidt, Grethe Jensen, Ruben Juhl Loya, Anand C. Lönn, Lars Birger Shekhrajka, Nitesh Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review |
title | Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review |
title_full | Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review |
title_fullStr | Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review |
title_full_unstemmed | Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review |
title_short | Preoperative Embolization of a Solitary Fibrous Tumor Originating from External Auditory Meatus: A Case Report with Literature Review |
title_sort | preoperative embolization of a solitary fibrous tumor originating from external auditory meatus: a case report with literature review |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823591/ https://www.ncbi.nlm.nih.gov/pubmed/33401743 http://dx.doi.org/10.3390/diagnostics11010062 |
work_keys_str_mv | AT ciochonurszulamaria preoperativeembolizationofasolitaryfibroustumororiginatingfromexternalauditorymeatusacasereportwithliteraturereview AT schmidtgrethe preoperativeembolizationofasolitaryfibroustumororiginatingfromexternalauditorymeatusacasereportwithliteraturereview AT jensenrubenjuhl preoperativeembolizationofasolitaryfibroustumororiginatingfromexternalauditorymeatusacasereportwithliteraturereview AT loyaanandc preoperativeembolizationofasolitaryfibroustumororiginatingfromexternalauditorymeatusacasereportwithliteraturereview AT lonnlarsbirger preoperativeembolizationofasolitaryfibroustumororiginatingfromexternalauditorymeatusacasereportwithliteraturereview AT shekhrajkanitesh preoperativeembolizationofasolitaryfibroustumororiginatingfromexternalauditorymeatusacasereportwithliteraturereview |