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Adipose-Derived Stem Cells from Obese Donors Polarize Macrophages and Microglia toward a Pro-Inflammatory Phenotype
Macrophages and microglia represent the primary phagocytes and first line of defense in the peripheral and central immune systems. They activate and polarize into a spectrum of pro- and anti-inflammatory phenotypes in response to various stimuli. This activation is tightly regulated to balance the a...
Autores principales: | Harrison, Mark A. A., Wise, Rachel M., Benjamin, Brooke P., Hochreiner, Emily M., Mohiuddin, Omair A., Bunnell, Bruce A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823699/ https://www.ncbi.nlm.nih.gov/pubmed/33375695 http://dx.doi.org/10.3390/cells10010026 |
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