Identification of New, Functionally Relevant Mutations in the Coding Regions of the Human Fos and Jun Proto-Oncogenes in Rheumatoid Arthritis Synovial Tissue

In rheumatoid arthritis (RA), the expression of many pro-destructive/pro-inflammatory proteins depends on the transcription factor AP-1. Therefore, our aim was to analyze the presence and functional relevance of mutations in the coding regions of the AP-1 subunits of the fos and jun family in periph...

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Detalles Bibliográficos
Autores principales: Huber, René, Augsten, Sandra, Kirsten, Holger, Zell, Roland, Stelzner, Axel, Thude, Hansjörg, Eidner, Thorsten, Stuhlmüller, Bruno, Ahnert, Peter, Kinne, Raimund W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823737/
https://www.ncbi.nlm.nih.gov/pubmed/33374881
http://dx.doi.org/10.3390/life11010005

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