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Poloxamer-188 and d-α-Tocopheryl Polyethylene Glycol Succinate (TPGS-1000) Mixed Micelles Integrated Orodispersible Sublingual Films to Improve Oral Bioavailability of Ebastine; In Vitro and In Vivo Characterization

Orodispersible sublingual films (OSFs) composed of hydrophilic polymers were loaded with poloxamer-188 and d-α-tocopheryl polyethylene glycol succinate (TPGS-1000) mixed micelles to improve the oral bioavailability of a poorly soluble drug, ebastine (EBT). Mixed micelles formed by thin-film hydratio...

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Detalles Bibliográficos
Autores principales:	Islam, Nayyer, Irfan, Muhammad, Khan, Salah-Ud-Din, Syed, Haroon Khalid, Iqbal, Muhammad Shahid, Khan, Ikram Ullah, Mahdy, Amina, Raafat, Mohamed, Hossain, Mohammad Akbar, Inam, Sana, Munir, Rabia, Ishtiaq, Memoona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823785/ https://www.ncbi.nlm.nih.gov/pubmed/33406587 http://dx.doi.org/10.3390/pharmaceutics13010054

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