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Study of Microchannels Fabricated Using Desktop Fused Deposition Modeling Systems

Microfluidic devices are used to transfer small quantities of liquid through micro-scale channels. Conventionally, these devices are fabricated using techniques such as soft-lithography, paper microfluidics, micromachining, injection moulding, etc. The advancement in modern additive manufacturing me...

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Autores principales: Rehmani, Muhammad Asif Ali, Jaywant, Swapna A., Arif, Khalid Mahmood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823880/
https://www.ncbi.nlm.nih.gov/pubmed/33375727
http://dx.doi.org/10.3390/mi12010014
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author Rehmani, Muhammad Asif Ali
Jaywant, Swapna A.
Arif, Khalid Mahmood
author_facet Rehmani, Muhammad Asif Ali
Jaywant, Swapna A.
Arif, Khalid Mahmood
author_sort Rehmani, Muhammad Asif Ali
collection PubMed
description Microfluidic devices are used to transfer small quantities of liquid through micro-scale channels. Conventionally, these devices are fabricated using techniques such as soft-lithography, paper microfluidics, micromachining, injection moulding, etc. The advancement in modern additive manufacturing methods is making three dimensional printing (3DP) a promising platform for the fabrication of microfluidic devices. Particularly, the availability of low-cost desktop 3D printers can produce inexpensive microfluidic devices in fast turnaround times. In this paper, we explore fused deposition modelling (FDM) to print non-transparent and closed internal micro features of in-plane microchannels (i.e., linear, curved and spiral channel profiles) and varying cross-section microchannels in the build direction (i.e., helical microchannel). The study provides a comparison of the minimum possible diameter size, the maximum possible fluid flow-rate without leakage, and absorption through the straight, curved, spiral and helical microchannels along with the printing accuracy of the FDM process for two low-cost desktop printers. Moreover, we highlight the geometry dependent printing issues of microchannels, pressure developed in the microchannels for complex geometry and establish that the profiles in which flowrate generates 4000 Pa are susceptible to leakages when no pre or post processing in the FDM printed parts is employed.
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spelling pubmed-78238802021-01-24 Study of Microchannels Fabricated Using Desktop Fused Deposition Modeling Systems Rehmani, Muhammad Asif Ali Jaywant, Swapna A. Arif, Khalid Mahmood Micromachines (Basel) Article Microfluidic devices are used to transfer small quantities of liquid through micro-scale channels. Conventionally, these devices are fabricated using techniques such as soft-lithography, paper microfluidics, micromachining, injection moulding, etc. The advancement in modern additive manufacturing methods is making three dimensional printing (3DP) a promising platform for the fabrication of microfluidic devices. Particularly, the availability of low-cost desktop 3D printers can produce inexpensive microfluidic devices in fast turnaround times. In this paper, we explore fused deposition modelling (FDM) to print non-transparent and closed internal micro features of in-plane microchannels (i.e., linear, curved and spiral channel profiles) and varying cross-section microchannels in the build direction (i.e., helical microchannel). The study provides a comparison of the minimum possible diameter size, the maximum possible fluid flow-rate without leakage, and absorption through the straight, curved, spiral and helical microchannels along with the printing accuracy of the FDM process for two low-cost desktop printers. Moreover, we highlight the geometry dependent printing issues of microchannels, pressure developed in the microchannels for complex geometry and establish that the profiles in which flowrate generates 4000 Pa are susceptible to leakages when no pre or post processing in the FDM printed parts is employed. MDPI 2020-12-25 /pmc/articles/PMC7823880/ /pubmed/33375727 http://dx.doi.org/10.3390/mi12010014 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Rehmani, Muhammad Asif Ali
Jaywant, Swapna A.
Arif, Khalid Mahmood
Study of Microchannels Fabricated Using Desktop Fused Deposition Modeling Systems
title Study of Microchannels Fabricated Using Desktop Fused Deposition Modeling Systems
title_full Study of Microchannels Fabricated Using Desktop Fused Deposition Modeling Systems
title_fullStr Study of Microchannels Fabricated Using Desktop Fused Deposition Modeling Systems
title_full_unstemmed Study of Microchannels Fabricated Using Desktop Fused Deposition Modeling Systems
title_short Study of Microchannels Fabricated Using Desktop Fused Deposition Modeling Systems
title_sort study of microchannels fabricated using desktop fused deposition modeling systems
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823880/
https://www.ncbi.nlm.nih.gov/pubmed/33375727
http://dx.doi.org/10.3390/mi12010014
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