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Production of Recombinant Monoclonal Antibodies in the Egg White of Gene-Targeted Transgenic Chickens

Increased commercial demand for monoclonal antibodies (mAbs) has resulted in the urgent need to establish efficient production systems. We previously developed a transgenic chicken bioreactor system that effectively produced human cytokines in egg whites using genome-edited transgenic chickens. Here...

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Detalles Bibliográficos
Autores principales: Mukae, Takehiro, Okumura, Sho, Watanobe, Takuma, Yoshii, Kyoko, Tagami, Takahiro, Oishi, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7823952/
https://www.ncbi.nlm.nih.gov/pubmed/33396657
http://dx.doi.org/10.3390/genes12010038