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A Screen for Small Molecules to Target Candida albicans Biofilms

The human fungal pathogen Candida albicans can form biofilms on biotic and abiotic surfaces, which are inherently resistant to antifungal drugs. We screened the Chembridge Small Molecule Diversity library containing 30,000 “drug-like” small molecules and identified 45 compounds that inhibited biofil...

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Detalles Bibliográficos
Autores principales: Lohse, Matthew B., Ennis, Craig L., Hartooni, Nairi, Johnson, Alexander D., Nobile, Clarissa J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824004/
https://www.ncbi.nlm.nih.gov/pubmed/33375490
http://dx.doi.org/10.3390/jof7010009