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A Screen for Small Molecules to Target Candida albicans Biofilms
The human fungal pathogen Candida albicans can form biofilms on biotic and abiotic surfaces, which are inherently resistant to antifungal drugs. We screened the Chembridge Small Molecule Diversity library containing 30,000 “drug-like” small molecules and identified 45 compounds that inhibited biofil...
Autores principales: | Lohse, Matthew B., Ennis, Craig L., Hartooni, Nairi, Johnson, Alexander D., Nobile, Clarissa J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824004/ https://www.ncbi.nlm.nih.gov/pubmed/33375490 http://dx.doi.org/10.3390/jof7010009 |
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