Cargando…

Aminoglycoside 6′-N-acetyltransferase Type Ib [AAC(6′)-Ib]-Mediated Aminoglycoside Resistance: Phenotypic Conversion to Susceptibility by Silver Ions

Clinical resistance to amikacin and other aminoglycosides is usually due to the enzymatic acetylation of the antimicrobial molecule. A ubiquitous resistance enzyme among Gram-negatives is the aminoglycoside 6′-N-acetyltransferase type Ib [AAC(6′)-Ib], which catalyzes acetylation using acetyl-CoA as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Reeves, Craig M., Magallon, Jesus, Rocha, Kenneth, Tran, Tung, Phan, Kimberly, Vu, Peter, Yi, Yang, Oakley-Havens, Crista L., Cedano, José, Jimenez, Verónica, Ramirez, Maria S., Tolmasky, Marcelo E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824292/ https://www.ncbi.nlm.nih.gov/pubmed/33396404 http://dx.doi.org/10.3390/antibiotics10010029

Ejemplares similares

Inhibition of Aminoglycoside 6′-N-acetyltransferase Type Ib (AAC(6′)-Ib): Structure–Activity Relationship of Substituted Pyrrolidine Pentamine Derivatives as Inhibitors
por: Rocha, Kenneth, et al.
Publicado: (2021)

Rise and dissemination of aminoglycoside resistance: the aac(6′)-Ib paradigm
por: Ramirez, María S., et al.
Publicado: (2013)

Aminoglycoside resistance profile and structural architecture of the aminoglycoside acetyltransferase AAC(6')-Im
por: Smith, Clyde A., et al.
Publicado: (2017)

Aminoglycoside Susceptibility Profiles of Enterobacter cloacae Isolates Harboring the aac(6')-Ib Gene
por: Kim, Soo-Young, et al.
Publicado: (2011)

Revisiting Polymorphic Diversity of Aminoglycoside N-Acetyltransferase AAC(6′)-Ib Based on Bacterial Genomes of Human, Animal, and Environmental Origins
por: Kim, Dae-Wi, et al.
Publicado: (2018)

Emergence of the Novel Aminoglycoside Acetyltransferase Variant aac(6′)-Ib-D179Y and Acquisition of Colistin Heteroresistance in Carbapenem-Resistant Klebsiella pneumoniae Due to a Disrupting Mutation in the DNA Repair Enzyme MutS
por: Sato, Toyotaka, et al.
Publicado: (2020)

Identification and characterization of a novel 6′-N-aminoglycoside acetyltransferase AAC(6′)-Va from a clinical isolate of Aeromonas hydrophila
por: Zhang, Guozhi, et al.
Publicado: (2023)

First Report of aac(6′)-Ib and aac(6′)-Ib-cr Variant Genes Associated with Mutations in gyrA Encoded Fluoroquinolone Resistance in Avian Campylobacter coli Strains Collected in Tunisia
por: Gharbi, Manel, et al.
Publicado: (2023)

The prevalence of aminoglycoside-modifying enzyme genes (aac (6′)-I, aac (6′)-II, ant (2″)-I, aph (3′)-VI) in Pseudomonas aeruginosa
por: Vaziri, Farzam, et al.
Publicado: (2011)

Detection of aac(6’)-Ib-cr in Avian Pathogenic Escherichia coli Isolates in Japan
por: KAWANISHI, Michiko, et al.
Publicado: (2013)

First report of the aac(6’)-Ib-cr gene in Providencia stuartii isolates in Brazil
por: da Silva, Sivoneide Maria, et al.
Publicado: (2020)

Stenotrophomonas maltophilia from Nepal Producing Two Novel Antibiotic Inactivating Enzymes, a Class A β-Lactamase KBL-1 and an Aminoglycoside 6′-N-Acetyltransferase AAC(6′)-Iap
por: Kawauchi, Ryota, et al.
Publicado: (2022)

Structural elucidation of substrate-bound aminoglycoside acetyltransferase (3)-IIIa
por: Zieliński, Michał, et al.
Publicado: (2022)

Epidemiologic, Phenotypic, and Structural Characterization of Aminoglycoside-Resistance Gene aac(3)-IV
por: Plattner, Michel, et al.
Publicado: (2020)

Amikacin potentiator activity of zinc complexed to a pyrithione derivative with enhanced solubility
por: Magallon, Jesus, et al.
Publicado: (2022)

Cooccurrence of NDM-1, ESBL, RmtC, AAC(6′)-Ib, and QnrB in Clonally Related Klebsiella pneumoniae Isolates Together with Coexistence of CMY-4 and AAC(6′)-Ib in Enterobacter cloacae Isolates from Saudi Arabia
por: Al-Agamy, Mohamed H., et al.
Publicado: (2019)

Prevalence of aac(6')-Ib-cr plasmid-mediated and chromosome-encoded fluoroquinolone resistance in Enterobacteriaceae in Italy
por: Frasson, Ilaria, et al.
Publicado: (2011)

Quinolone Susceptibility and Detection of qnr and aac(6’)-Ib-cr Genes in Community Isolates of Klebsiella pneumoniae
por: Seyedpour, Seyed Mohsen, et al.
Publicado: (2014)

ApmA Is a Unique Aminoglycoside Antibiotic Acetyltransferase That Inactivates Apramycin
por: Bordeleau, Emily, et al.
Publicado: (2021)

Structural and phylogenetic analyses of resistance to next-generation aminoglycosides conferred by AAC(2′) enzymes
por: Bassenden, Angelia V., et al.
Publicado: (2021)

Characterization and Molecular Mechanism of Aminoglycoside-6-Adenyl Transferase Associated with Aminoglycoside Resistance from Elizabethkingia meningoseptica
por: Zhang, Shaoxing, et al.
Publicado: (2023)

PMQR genes oqxAB and aac(6′)Ib-cr accelerate the development of fluoroquinolone resistance in Salmonella typhimurium
por: Wong, Marcus H., et al.
Publicado: (2014)

Aminoglycosides: Molecular Insights on the Recognition of RNA and Aminoglycoside Mimics
por: Chittapragada, Maruthi, et al.
Publicado: (2009)

Structural and biochemical analyses of an aminoglycoside 2′-N-acetyltransferase from Mycolicibacterium smegmatis
por: Jeong, Chang-Sook, et al.
Publicado: (2020)

Identification and Characterization of a Novel Chromosomal Aminoglycoside 2′-N-Acetyltransferase, AAC(2′)-If, From an Isolate of a Novel Providencia Species, Providencia wenzhouensis R33
por: Zhou, Kexin, et al.
Publicado: (2021)

Increasing Prevalence of Aminoglycoside-Resistant Enterococcus faecalis Isolates Due to the aac(6’)-aph(2”) Gene: A Therapeutic Problem in Kermanshah, Iran
por: Khani, Mitra, et al.
Publicado: (2016)

Mycobacterial Aminoglycoside Acetyltransferases: A Little of Drug Resistance, and a Lot of Other Roles
por: Sanz-García, Fernando, et al.
Publicado: (2019)

Resistome analysis of Mycobacterium tuberculosis: Identification of aminoglycoside 2'-Nacetyltransferase (AAC) as co-target for drug desigining
por: Joshi, Rakesh S, et al.
Publicado: (2013)

Susceptibility to Aminoglycosides and Distribution of aph and aac(3)-XI Genes among Corynebacterium striatum Clinical Isolates
por: Navas, Jesús, et al.
Publicado: (2016)

Aminoglycoside riboswitch control of the expression of integron associated aminoglycoside resistance adenyltransferases
por: Zhang, Jun, et al.
Publicado: (2020)

Prevalence of qnr and aac(6’)-Ib-cr Genes in Clinical Isolates of Klebsiella Pneumoniae from Imam Hussein Hospital in Tehran
por: Eftekhar, Fereshteh, et al.
Publicado: (2015)

Aminoglycoside Allergic Reactions
por: Childs-Kean, Lindsey M., et al.
Publicado: (2019)

Aminoglycoside resistance mechanism inference algorithm: Implication for underlying resistance mechanisms to aminoglycosides
por: Touati, Abdelaziz
Publicado: (2019)

Derivatization of Aminoglycoside Antibiotics with Tris(2,6-dimethoxyphenyl)carbenium Ion
por: Topolyan, A.P., et al.
Publicado: (2016)

Silver nanoparticles enhance the efficacy of aminoglycosides against antibiotic-resistant bacteria
por: Dove, Autumn S., et al.
Publicado: (2023)

High Prevalence of qnr and aac(6′)-Ib-cr Genes in Both Water-Borne Environmental Bacteria and Clinical Isolates of Citrobacter freundii in China
por: Zhang, Rong, et al.
Publicado: (2012)

QnrS1- and Aac(6′)-Ib-cr-Producing Escherichia coli among Isolates from Animals of Different Sources: Susceptibility and Genomic Characterization
por: Jones-Dias, Daniela, et al.
Publicado: (2016)

Clinical and Molecular Epidemiology of Multidrug-Resistant P. aeruginosa Carrying aac(6')-Ib-cr, qnrS1 and bla(SPM) Genes in Brazil
por: Araujo, Bruna Fuga, et al.
Publicado: (2016)

Aminoglycoside use in renal failure
por: Nayak-Rao, S.
Publicado: (2010)

Aminoglycoside-induced nephrotoxicity in children
por: McWilliam, Stephen J, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_lqus5r6jhb6dcviralqu6pptrv