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Expanding the Structural Diversity of DNA Methyltransferase Inhibitors

Inhibitors of DNA methyltransferases (DNMTs) are attractive compounds for epigenetic drug discovery. They are also chemical tools to understand the biochemistry of epigenetic processes. Herein, we report five distinct inhibitors of DNMT1 characterized in enzymatic inhibition assays that did not show...

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Detalles Bibliográficos
Autores principales: Juárez-Mercado, K. Eurídice, Prieto-Martínez, Fernando D., Sánchez-Cruz, Norberto, Peña-Castillo, Andrea, Prada-Gracia, Diego, Medina-Franco, José L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824300/
https://www.ncbi.nlm.nih.gov/pubmed/33375520
http://dx.doi.org/10.3390/ph14010017

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