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Expanding the Structural Diversity of DNA Methyltransferase Inhibitors
Inhibitors of DNA methyltransferases (DNMTs) are attractive compounds for epigenetic drug discovery. They are also chemical tools to understand the biochemistry of epigenetic processes. Herein, we report five distinct inhibitors of DNMT1 characterized in enzymatic inhibition assays that did not show...
Autores principales: | Juárez-Mercado, K. Eurídice, Prieto-Martínez, Fernando D., Sánchez-Cruz, Norberto, Peña-Castillo, Andrea, Prada-Gracia, Diego, Medina-Franco, José L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824300/ https://www.ncbi.nlm.nih.gov/pubmed/33375520 http://dx.doi.org/10.3390/ph14010017 |
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