RET Copy Number Alteration in Medullary Thyroid Cancer Is a Rare Event Correlated with RET Somatic Mutations and High Allelic Frequency

Copy number variations (CNV) of the RET gene have been described in 30% of Medullary Thyroid Cancer (MTC), but no information is available about their role in this tumor. This study was designed to clarify RET gene CNV prevalence and their potential role in MTC development. RET gene CNV were analyze...

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Detalles Bibliográficos
Autores principales: Ramone, Teresa, Mulè, Chiara, Ciampi, Raffaele, Bottici, Valeria, Cappagli, Virginia, Prete, Alessandro, Matrone, Antonio, Piaggi, Paolo, Torregrossa, Liborio, Basolo, Fulvio, Elisei, Rossella, Romei, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824333/
https://www.ncbi.nlm.nih.gov/pubmed/33383911
http://dx.doi.org/10.3390/genes12010035

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