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Sensitivity Analysis of Biosensors Based on a Dielectric-Modulated L-Shaped Gate Field-Effect Transistor

Label-free biomolecular sensors have been widely studied due to their simple operation. L-shaped tunneling field-effect transistors (LTFETs) are used in biosensors due to their low subthreshold swing, off-state current, and power consumption. In a dielectric-modulated LTFET (DM-LTFET), a cavity is t...

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Autores principales: Chong, Chen, Liu, Hongxia, Wang, Shulong, Chen, Shupeng, Xie, Haiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824392/
https://www.ncbi.nlm.nih.gov/pubmed/33375411
http://dx.doi.org/10.3390/mi12010019
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author Chong, Chen
Liu, Hongxia
Wang, Shulong
Chen, Shupeng
Xie, Haiwu
author_facet Chong, Chen
Liu, Hongxia
Wang, Shulong
Chen, Shupeng
Xie, Haiwu
author_sort Chong, Chen
collection PubMed
description Label-free biomolecular sensors have been widely studied due to their simple operation. L-shaped tunneling field-effect transistors (LTFETs) are used in biosensors due to their low subthreshold swing, off-state current, and power consumption. In a dielectric-modulated LTFET (DM-LTFET), a cavity is trenched under the gate electrode in the vertical direction and filled with biomolecules to realize the function of the sensor. A 2D simulator was utilized to study the sensitivity of a DM-LTFET sensor. The simulation results show that the current sensitivity of the proposed structure could be as high as 2321, the threshold voltage sensitivity could reach 0.4, and the subthreshold swing sensitivity could reach 0.7. This shows that the DM-LTFET sensor is suitable for a high-sensitivity, low-power-consumption sensor field.
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spelling pubmed-78243922021-01-24 Sensitivity Analysis of Biosensors Based on a Dielectric-Modulated L-Shaped Gate Field-Effect Transistor Chong, Chen Liu, Hongxia Wang, Shulong Chen, Shupeng Xie, Haiwu Micromachines (Basel) Article Label-free biomolecular sensors have been widely studied due to their simple operation. L-shaped tunneling field-effect transistors (LTFETs) are used in biosensors due to their low subthreshold swing, off-state current, and power consumption. In a dielectric-modulated LTFET (DM-LTFET), a cavity is trenched under the gate electrode in the vertical direction and filled with biomolecules to realize the function of the sensor. A 2D simulator was utilized to study the sensitivity of a DM-LTFET sensor. The simulation results show that the current sensitivity of the proposed structure could be as high as 2321, the threshold voltage sensitivity could reach 0.4, and the subthreshold swing sensitivity could reach 0.7. This shows that the DM-LTFET sensor is suitable for a high-sensitivity, low-power-consumption sensor field. MDPI 2020-12-27 /pmc/articles/PMC7824392/ /pubmed/33375411 http://dx.doi.org/10.3390/mi12010019 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chong, Chen
Liu, Hongxia
Wang, Shulong
Chen, Shupeng
Xie, Haiwu
Sensitivity Analysis of Biosensors Based on a Dielectric-Modulated L-Shaped Gate Field-Effect Transistor
title Sensitivity Analysis of Biosensors Based on a Dielectric-Modulated L-Shaped Gate Field-Effect Transistor
title_full Sensitivity Analysis of Biosensors Based on a Dielectric-Modulated L-Shaped Gate Field-Effect Transistor
title_fullStr Sensitivity Analysis of Biosensors Based on a Dielectric-Modulated L-Shaped Gate Field-Effect Transistor
title_full_unstemmed Sensitivity Analysis of Biosensors Based on a Dielectric-Modulated L-Shaped Gate Field-Effect Transistor
title_short Sensitivity Analysis of Biosensors Based on a Dielectric-Modulated L-Shaped Gate Field-Effect Transistor
title_sort sensitivity analysis of biosensors based on a dielectric-modulated l-shaped gate field-effect transistor
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824392/
https://www.ncbi.nlm.nih.gov/pubmed/33375411
http://dx.doi.org/10.3390/mi12010019
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