PSGL-1 Inhibits the Incorporation of SARS-CoV and SARS-CoV-2 Spike Glycoproteins into Pseudovirions and Impairs Pseudovirus Attachment and Infectivity

P-selectin glycoprotein ligand-1 (PSGL-1) is a cell surface glycoprotein that binds to P-, E-, and L-selectins to mediate the tethering and rolling of immune cells on the surface of the endothelium for cell migration into inflamed tissues. PSGL-1 has been identified as an interferon-γ (INF-γ)-regula...

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Detalles Bibliográficos
Autores principales: He, Sijia, Waheed, Abdul A., Hetrick, Brian, Dabbagh, Deemah, Akhrymuk, Ivan V., Kehn-Hall, Kylene, Freed, Eric O., Wu, Yuntao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824426/
https://www.ncbi.nlm.nih.gov/pubmed/33396594
http://dx.doi.org/10.3390/v13010046

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