Cargando…

Detection of Active BoNT/C and D by EndoPep-MS Using MALDI Biotyper Instrument and Comparison with the Mouse Test Bioassay

Botulinum neurotoxins (BoNTs) are among the most poisonous known biological substances, and therefore the availability of reliable, easy-to use tools for BoNT detection are important goals for food safety and human and animal health. The reference method for toxin detection and identification is the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Drigo, Ilenia, Tonon, Elena, Pascoletti, Simone, Anniballi, Fabrizio, Kalb, Suzanne R., Bano, Luca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824663/ https://www.ncbi.nlm.nih.gov/pubmed/33374240 http://dx.doi.org/10.3390/toxins13010010

Ejemplares similares

Extraction of BoNT/A, /B, /E, and /F with a Single, High Affinity Monoclonal Antibody for Detection of Botulinum Neurotoxin by Endopep-MS
por: Kalb, Suzanne R., et al.
Publicado: (2010)

Further optimization of peptide substrate enhanced assay performance for BoNT/A detection by MALDI-TOF mass spectrometry
por: Wang, Dongxia, et al.
Publicado: (2017)

Navigating the Complexities Involving the Identification of Botulinum Neurotoxins (BoNTs) and the Taxonomy of BoNT-Producing Clostridia
por: Smith, Theresa J., et al.
Publicado: (2023)

Mucosal Targeting of a BoNT/A Subunit Vaccine Adjuvanted with a Mast Cell Activator Enhances Induction of BoNT/A Neutralizing Antibodies in Rabbits
por: Staats, Herman F., et al.
Publicado: (2011)

The Effects of Intradetrusor BoNT-A Injections on Vesicoureteral Reflux in Children With Myelodysplasia
por: Toprak, Tuncay, et al.
Publicado: (2019)

Exploring the genetic background of the botulism neurotoxin BoNT/B2 in Spain
por: Valdezate, Sylvia, et al.
Publicado: (2023)

BoNT/A in the Urinary Bladder—More to the Story than Silencing of Cholinergic Nerves
por: Ibrahim, Hodan, et al.
Publicado: (2022)

A novel RRGW derived peptide is a promising inhibitor of BoNT/A
por: Ma, Wantong, et al.
Publicado: (2023)

Searching for the Predictors of Response to BoNT-A in Migraine Using Machine Learning Approaches
por: Martinelli, Daniele, et al.
Publicado: (2023)

Small-Molecule Quinolinol Inhibitor Identified Provides Protection against BoNT/A in Mice
por: Singh, Padma, et al.
Publicado: (2012)

Probing BoNT/A Protease Exosites: Implications for Inhibitor Design and Light Chain Longevity
por: Xue, Song, et al.
Publicado: (2014)

Clinical analysis of 86 botulism cases caused by cosmetic injection of botulinum toxin (BoNT)
por: Bai, Lili, et al.
Publicado: (2018)

Botulinum neurotoxin (BoNT) treatment in functional movement disorders: long-term follow-up
por: Dreissen, Yasmine EM, et al.
Publicado: (2020)

A Three-Monoclonal Antibody Combination Potently Neutralizes BoNT/G Toxin in Mice
por: Fan, Yongfeng, et al.
Publicado: (2023)

Recombinant Botulinum Neurotoxin Hc Subunit (BoNT Hc) and Catalytically Inactive Clostridium botulinum Holoproteins (ciBoNT HPs) as Vaccine Candidates for the Prevention of Botulism
por: Webb, Robert P., et al.
Publicado: (2017)

Reduction in expenditures on analgesics during one year of treatment of chronic tension headache with BoNT-A
por: Coloprisco, Gabriella, et al.
Publicado: (2003)

Hypersensitive Detection and Quantitation of BoNT/A by IgY Antibody against Substrate Linear-Peptide
por: Li, Tao, et al.
Publicado: (2013)

Retraction: Small-Molecule Quinolinol Inhibitor Identified Provides Protection against BoNT/A in Mice
por: Singh, Padma, et al.
Publicado: (2013)

Designing and analyzing the structure of Tat-BoNT/A(1-448) fusion protein: An in silico approach
por: Amani, Jafar, et al.
Publicado: (2014)

The Novel Clostridial Neurotoxin Produced by Strain IBCA10-7060 Is Immunologically Equivalent to BoNT/HA
por: Fan, Yongfeng, et al.
Publicado: (2019)

Plasma Levels of Oxidative Stress Markers, before and after BoNT/A Treatment, in Chronic Migraine
por: Dini, Elisa, et al.
Publicado: (2019)

Preclinical Evidence for the Role of Botulinum Neurotoxin A (BoNT/A) in the Treatment of Peripheral Nerve Injury
por: Adler, Michael, et al.
Publicado: (2022)

Botulinum Neurotoxins (BoNTs)—Antibody and Vaccine
por: Lou, Jianlong, et al.
Publicado: (2018)

Effect of BoNT/A in the Surface Electromyographic Characteristics of the Pelvic Floor Muscles for the Treatment of Chronic Pelvic Pain
por: Albaladejo-Belmonte, Monica, et al.
Publicado: (2021)

BoNT/A1 Secondary Failure for the Treatment of Neurogenic Detrusor Overactivity: An Ex Vivo Functional Study
por: Maignel, Jacquie, et al.
Publicado: (2022)

Adjunctive treatment and BoNT-A for post-stroke spasticity: Are we really focusing on the patient-centered goals?
por: Baricich, Alessio, et al.
Publicado: (2023)

The Efficacy of Transvaginal Ultrasound-Guided BoNT-A External Sphincter Injection in Female Patients with Underactive Bladder
por: Tsai, Cheng-Yen, et al.
Publicado: (2023)

Extraction and Inhibition of Enzymatic Activity of Botulinum Neurotoxins/A1, /A2, and /A3 by a Panel of Monoclonal Anti-BoNT/A Antibodies
por: Kalb, Suzanne R., et al.
Publicado: (2009)

Human-Relevant Sensitivity of iPSC-Derived Human Motor Neurons to BoNT/A1 and B1
por: Schenke, Maren, et al.
Publicado: (2021)

BoNT-A for Post-Stroke Spasticity: Guidance on Unmet Clinical Needs from a Delphi Panel Approach
por: Baricich, Alessio, et al.
Publicado: (2021)

Subcutaneous BoNT/A Injection for Intractable Pain and Disability in Complex Regional Pain Syndrome: A Case Report
por: Tereshko, Yan, et al.
Publicado: (2022)

Comparison of botulinum toxin (BoNT) injection and lateral internal sphincterotomy (redo-LIS) for recurrent anal fissure treatment
por: Alyanak, Ahmet, et al.
Publicado: (2022)

Multicolor fluorescence activated cell sorting to generate humanized monoclonal antibody binding seven subtypes of BoNT/F
por: Fan, Yongfeng, et al.
Publicado: (2022)

Reasons and Determinants of BoNT-A Treatment Discontinuation in Patients Living with Spasticity: A 10-Year Retrospective Analysis
por: Cinone, Nicoletta, et al.
Publicado: (2022)

Outbreaks of iatrogenic botulism in Europe: Combating off-label medical use of Botulinum Neurotoxin (BoNT) in bariatric procedures
por: Jain, Nityanand, et al.
Publicado: (2023)

Alpha-Latrotoxin Rescues SNAP-25 from BoNT/A-Mediated Proteolysis in Embryonic Stem Cell-Derived Neurons
por: Mesngon, Mariano, et al.
Publicado: (2011)

Anti-Inflammatory Effects of BoNT/A Against Complete Freund’s Adjuvant-Induced Arthritis Pain in Rats: Transcriptome Analysis
por: Li, Xinhe, et al.
Publicado: (2021)

Extraction and inhibition of enzymatic activity of botulinum neurotoxins /B1, /B2, /B3, /B4, and /B5 by a panel of monoclonal anti-BoNT/B antibodies
por: Kalb, Suzanne R, et al.
Publicado: (2011)

Identification of Fibroblast Growth Factor Receptor 3 (FGFR3) as a Protein Receptor for Botulinum Neurotoxin Serotype A (BoNT/A)
por: Jacky, Birgitte P. S., et al.
Publicado: (2013)

Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C
por: Benoit, Roger M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_fhdgllqg549126e0l6a1acta4r