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Identification of Targets from LRRK2 Rescue Phenotypes

Parkinson’s disease (PD) is an age-dependent neurodegenerative condition. Leucine-rich repeat kinase 2 (LRRK2) mutations are the most frequent cause of sporadic and autosomal dominant PD. The exact role of LRRK2 protective variants (R1398H, N551K) together with a pathogenic mutant (G2019S) in aging...

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Detalles Bibliográficos
Autores principales:	Toh, Joanne, Chua, Ling Ling, Ho, Patrick, Sandanaraj, Edwin, Tang, Carol, Wang, Hongyan, Tan, Eng King
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824855/ https://www.ncbi.nlm.nih.gov/pubmed/33466414 http://dx.doi.org/10.3390/cells10010076

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