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Population-Specific ACE2 Single-Nucleotide Polymorphisms Have Limited Impact on SARS-CoV-2 Infectivity In Vitro

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), employs host-cell angiotensin-converting enzyme 2 (ACE2) for cell entry. Genetic analyses of ACE2 have identified several single-nucleotide polymorphisms (SNPs) specific to diffe...

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Detalles Bibliográficos
Autores principales: Hashizume, Mei, Gonzalez, Gabriel, Ono, Chikako, Takashima, Ayako, Iwasaki, Masaharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825141/
https://www.ncbi.nlm.nih.gov/pubmed/33418950
http://dx.doi.org/10.3390/v13010067

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