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Cohesin promotes HSV-1 lytic transcription by facilitating the binding of RNA Pol II on viral genes

BACKGROUND: Herpes Simplex Virus type I (HSV-1) is a large double-stranded DNA virus that enters productive infection in epithelial cells and reorganizes the host nucleus. Cohesin, a major constituent of interphase and mitotic chromosomes comprised of SMC1, SMC3, and SCC1 (Mcd1/Rad21), SCC3 (SA1/SA2...

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Detalles Bibliográficos
Autores principales: Li, Xin, Yu, Yafen, Lang, Fengchao, Chen, Guijun, Wang, Erlin, Li, Lihong, Li, Zhuoran, Yang, Liping, Cao, Xia, Fraser, Nigel W., Zhou, Jumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825184/
https://www.ncbi.nlm.nih.gov/pubmed/33485391
http://dx.doi.org/10.1186/s12985-021-01495-2