Cargando…
Longitudinal Tumor Size and Neutrophil‐to‐Lymphocyte Ratio Are Prognostic Biomarkers for Overall Survival in Patients With Advanced Non‐Small Cell Lung Cancer Treated With Durvalumab
Therapy optimization remains an important challenge in the treatment of advanced non‐small cell lung cancer (NSCLC). We investigated tumor size (sum of the longest diameters (SLD) of target lesions) and neutrophil‐to‐lymphocyte ratio (NLR) as longitudinal biomarkers for survival prediction. Data set...
Autores principales: | Gavrilov, Sergey, Zhudenkov, Kirill, Helmlinger, Gabriel, Dunyak, James, Peskov, Kirill, Aksenov, Sergey |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825193/ https://www.ncbi.nlm.nih.gov/pubmed/33319498 http://dx.doi.org/10.1002/psp4.12578 |
Ejemplares similares
-
A workflow for the joint modeling of longitudinal and event data in the development of therapeutics: Tools, statistical methods, and diagnostics
por: Zhudenkov, Kirill, et al.
Publicado: (2022) -
Interpretation of metabolic memory phenomenon using a physiological systems model: What drives oxidative stress following glucose normalization?
por: Voronova, Veronika, et al.
Publicado: (2017) -
Longitudinal FEV(1) and Exacerbation Risk in COPD: Quantifying the Association Using Joint Modelling
por: Zhudenkov, Kirill, et al.
Publicado: (2021) -
Comparative quantitative systems pharmacology modeling of anti-PCSK9 therapeutic modalities in hypercholesterolemia
por: Sokolov, Victor, et al.
Publicado: (2019) -
Dose dependence of treatment-related adverse events for immune checkpoint inhibitor therapies: a model-based meta-analysis
por: Shulgin, Boris, et al.
Publicado: (2020)