Cargando…

Role of epidermal growth factor receptor inhibitor-induced interferon pathway signaling in the head and neck squamous cell carcinoma therapeutic response

BACKGROUND: Epidermal growth factor receptor (EGFR) is frequently amplified or overexpressed in head and neck squamous cell carcinoma (HNSCC) and is a clinically validated target for the therapeutic antibody, cetuximab, in the management of this cancer. The degree of response to EGFR inhibitors meas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Korpela, Sean P., Hinz, Trista K., Oweida, Ayman, Kim, Jihye, Calhoun, Jacob, Ferris, Robert, Nemenoff, Raphael A., Karam, Sana D., Clambey, Eric T., Heasley, Lynn E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825244/ https://www.ncbi.nlm.nih.gov/pubmed/33485341 http://dx.doi.org/10.1186/s12967-021-02706-8

Ejemplares similares

A tyrosine kinase inhibitor-induced interferon response positively associates with clinical response in EGFR-mutant lung cancer
por: Gurule, Natalia J., et al.
Publicado: (2021)

Evaluation of KRAS(G12C) inhibitor responses in novel murine KRAS(G12C) lung cancer cell line models
por: Sisler, Daniel J., et al.
Publicado: (2023)

Enhancing radiosensitization in EphB4 receptor-expressing Head and Neck Squamous Cell Carcinomas
por: Bhatia, Shilpa, et al.
Publicado: (2016)

A Rapid, Functional sgRNA Screening Method for Generating Murine RET and NTRK1 Fusion Oncogenes
por: Schubert, Laura, et al.
Publicado: (2023)

A functional sgRNA-CRISPR screening method for generating murine RET and NTRK1 rearranged oncogenes
por: Schubert, Laura, et al.
Publicado: (2023)

Durable responses to alectinib in murine models of EML4-ALK lung cancer requires adaptive immunity
por: Kleczko, Emily K., et al.
Publicado: (2023)

Overcoming Resistance to Combination Radiation-Immunotherapy: A Focus on Contributing Pathways Within the Tumor Microenvironment
por: Darragh, Laurel B., et al.
Publicado: (2019)

Immunotherapy for Head and Neck Squamous Cell Carcinoma
por: Moskovitz, Jessica, et al.
Publicado: (2018)

Rapidly Acquired Resistance to EGFR Tyrosine Kinase Inhibitors in NSCLC Cell Lines through De-Repression of FGFR2 and FGFR3 Expression
por: Ware, Kathryn E., et al.
Publicado: (2010)

Complement C3a and C5a receptor blockade modulates regulatory T cell conversion in head and neck cancer
por: Gadwa, Jacob, et al.
Publicado: (2021)

EphB4 and ephrinB2 act in opposition in the head and neck tumor microenvironment
por: Bhatia, Shilpa, et al.
Publicado: (2022)

Mtss1 regulates epidermal growth factor signaling in head and neck squamous carcinoma cells
por: Dawson, John C., et al.
Publicado: (2011)

The Use of Epidermal Growth Factor Receptor Monoclonal Antibodies in Squamous Cell Carcinoma of the Head and Neck
por: Russell, Jeffery S., et al.
Publicado: (2012)

Bleeding complications in patients with squamous cell carcinoma of the head and neck
por: Bergamini, Cristiana, et al.
Publicado: (2021)

Interferon Regulatory Factor Family Genes: At the Crossroads between Immunity and Head and Neck Squamous Carcinoma
por: Liu, Shaokun, et al.
Publicado: (2022)

Honokiol inhibits the growth of head and neck squamous cell carcinoma by targeting epidermal growth factor receptor
por: Singh, Tripti, et al.
Publicado: (2015)

The effect of second hand smoke in patients with squamous cell carcinoma of the head and neck
por: Idris, Sherif, et al.
Publicado: (2019)

Epidermal growth factor receptor expression by human squamous cell carcinomas of the head and neck, cell lines and xenografts.
por: Stanton, P., et al.
Publicado: (1994)

Exons 19 and 21 of Epidermal Growth Factor Receptor Are Highly Conserved in Squamous Cell Cancer of the Head and Neck
por: Carlson, Matthew, et al.
Publicado: (2009)

Balancing Safety and Efficacy of Epidermal Growth Factor Receptor Inhibitors in Patients With Squamous Cell Carcinoma of the Head and Neck
por: Iberri, David J., et al.
Publicado: (2016)

RhoC Mediates Epidermal Growth Factor-Stimulated Migration and Invasion in Head and Neck Squamous Cell Carcinoma
por: Tumur, Zohra, et al.
Publicado: (2015)

Cancer cell-intrinsic expression of MHC II in lung cancer cell lines is actively restricted by MEK/ERK signaling and epigenetic mechanisms
por: Neuwelt, Alexander J, et al.
Publicado: (2020)

Immunotherapy in head and neck squamous cell carcinoma and rare head and neck malignancies
por: Cavalieri, Stefano, et al.
Publicado: (2021)

SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck
por: Nigam, Nupur, et al.
Publicado: (2023)

Prognostic significance of cortactin levels in head and neck squamous cell carcinoma: comparison with epidermal growth factor receptor status
por: Hofman, P, et al.
Publicado: (2008)

Meta-analysis of the effects of anti-epidermal growth factor receptor on recurrent/metastatic head and neck squamous cell carcinoma
por: Xin, Yong, et al.
Publicado: (2018)

Epidermal growth factor receptor variant III in head and neck squamous cell carcinoma is not relevant for targeted therapy and irradiation
por: Koch, Dominik Thomas, et al.
Publicado: (2017)

MERTK as a novel therapeutic target in head and neck cancer
por: von Mässenhausen, Anne, et al.
Publicado: (2016)

Overcoming Resistance to Immunotherapy in Head and Neck Cancer Using Radiation: A Review
por: Hui, Caressa, et al.
Publicado: (2021)

Measurement of mouse head and neck tumors by automated analysis of CBCT images
por: Van Court, Benjamin, et al.
Publicado: (2023)

Tumor hypoxia is associated with resistance to PD-1 blockade in squamous cell carcinoma of the head and neck
por: Zandberg, Dan P, et al.
Publicado: (2021)

Epidermal growth factor-induced ANGPTL4 enhances anoikis resistance and tumour metastasis in head and neck squamous cell carcinoma
por: Liao, Y-H, et al.
Publicado: (2017)

Evaluation of Methylation Profiles of An Epidermal Growth Factor Receptor Gene in a Head and Neck Squamous Cell Carcinoma Patient Group
por: Mutlu, M, et al.
Publicado: (2021)

Interferon-alpha promotes immunosuppression through IFNAR1/STAT1 signalling in head and neck squamous cell carcinoma
por: Ma, Hailong, et al.
Publicado: (2018)

Definitive local therapy to head and neck squamous cell carcinoma with distant metastasis
por: Borson, Steven, et al.
Publicado: (2022)

Radiosensitization of head and neck cancer by targeting the epidermal growth factor receptor
por: Goel, Arun Kumar, et al.
Publicado: (2009)

Toxic epidermal necrolysis associated with nivolumab treatment for head and neck cancer
por: Koshizuka, Keiichi, et al.
Publicado: (2020)

Cutaneous Squamous Cell Carcinoma of the Head and Neck
por: Gurudutt, Vivek V., et al.
Publicado: (2011)

Hypoxia in Head and Neck Squamous Cell Carcinoma
por: Li, John Zenghong, et al.
Publicado: (2012)

Immunotherapy for head and neck squamous cell carcinoma
por: Fuereder, Thorsten
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ipjaspo29vq7l1n1dh5i0u29p0