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Experimental dopaminergic neuron lesion at the area of the biological clock pacemaker, suprachiasmatic nuclei (SCN) induces metabolic syndrome in rats

BACKGROUND: The daily peak in dopaminergic neuronal activity at the area of the biological clock (hypothalamic suprachiasmatic nuclei [SCN]) is diminished in obese/insulin resistant vs lean/insulin sensitive animals. The impact of targeted lesioning of dopamine (DA) neurons specifically at the area...

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Detalles Bibliográficos
Autores principales:	Luo, Shuqin, Ezrokhi, Michael, Cominos, Nicholas, Tsai, Tsung-Huang, Stoelzel, Carl R., Trubitsyna, Yelena, Cincotta, Anthony H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825247/ https://www.ncbi.nlm.nih.gov/pubmed/33485386 http://dx.doi.org/10.1186/s13098-021-00630-x

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