Cargando…

The Role of Cellular Prion Protein in Promoting Stemness and Differentiation in Cancer

SIMPLE SUMMARY: Aside from its well-established role in prion disorders, in the last decades the significance of cellular prion protein (PrP(C)) expression in human cancers has attracted great attention. An extensive body of work provided evidence that PrP(C) contributes to tumorigenesis by regulati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ryskalin, Larisa, Biagioni, Francesca, Busceti, Carla L., Giambelluca, Maria A., Morelli, Luca, Frati, Alessandro, Fornai, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825291/ https://www.ncbi.nlm.nih.gov/pubmed/33418999 http://dx.doi.org/10.3390/cancers13020170

Ejemplares similares

Prion Protein in Glioblastoma Multiforme
por: Ryskalin, Larisa, et al.
Publicado: (2019)

The Role of Cellular Prion Protein in Glioma Tumorigenesis Could Be through the Autophagic Mechanisms: A Narrative Review
por: Armocida, Daniele, et al.
Publicado: (2023)

The Multi-Faceted Effect of Curcumin in Glioblastoma from Rescuing Cell Clearance to Autophagy-Independent Effects
por: Ryskalin, Larisa, et al.
Publicado: (2020)

Spreading of Alpha Synuclein from Glioblastoma Cells towards Astrocytes Correlates with Stem-like Properties
por: Ryskalin, Larisa, et al.
Publicado: (2022)

Phytochemicals Bridging Autophagy Induction and Alpha-Synuclein Degradation in Parkinsonism
por: Limanaqi, Fiona, et al.
Publicado: (2019)

Cell Clearing Systems Bridging Neuro-Immunity and Synaptic Plasticity
por: Limanaqi, Fiona, et al.
Publicado: (2019)

Lactoferrin Protects against Methamphetamine Toxicity by Modulating Autophagy and Mitochondrial Status
por: Ryskalin, Larisa, et al.
Publicado: (2021)

Molecular Mechanisms Linking ALS/FTD and Psychiatric Disorders, the Potential Effects of Lithium
por: Limanaqi, Fiona, et al.
Publicado: (2019)

mTOR-Related Brain Dysfunctions in Neuropsychiatric Disorders
por: Ryskalin, Larisa, et al.
Publicado: (2018)

Occurrence of Total and Proteinase K-Resistant Alpha-Synuclein in Glioblastoma Cells Depends on mTOR Activity
por: Ryskalin, Larisa, et al.
Publicado: (2022)

The Autophagy Status of Cancer Stem Cells in Gliobastoma Multiforme: From Cancer Promotion to Therapeutic Strategies
por: Ryskalin, Larisa, et al.
Publicado: (2019)

mTOR Modulates Intercellular Signals for Enlargement and Infiltration in Glioblastoma Multiforme
por: Ryskalin, Larisa, et al.
Publicado: (2020)

A Focus on the Beneficial Effects of Alpha Synuclein and a Re-Appraisal of Synucleinopathies
por: Ryskalin, Larisa, et al.
Publicado: (2018)

The Effects of Amphetamine and Methamphetamine on the Release of Norepinephrine, Dopamine and Acetylcholine From the Brainstem Reticular Formation
por: Ferrucci, Michela, et al.
Publicado: (2019)

Inhibition of Autophagy In Vivo Extends Methamphetamine Toxicity to Mesencephalic Cell Bodies
por: Ferrucci, Michela, et al.
Publicado: (2021)

Ultrastructural characterization of peripheral denervation in a mouse model of Type III spinal muscular atrophy
por: Fulceri, Federica, et al.
Publicado: (2021)

The Autophagy-Related Organelle Autophagoproteasome Is Suppressed within Ischemic Penumbra
por: Biagioni, Francesca, et al.
Publicado: (2021)

mTOR-Dependent Cell Proliferation in the Brain
por: Ryskalin, Larisa, et al.
Publicado: (2017)

Ambiguous Effects of Autophagy Activation Following Hypoperfusion/Ischemia
por: Ferrucci, Michela, et al.
Publicado: (2018)

The Neuroanatomy of the Reticular Nucleus Locus Coeruleus in Alzheimer’s Disease
por: Giorgi, Filippo S., et al.
Publicado: (2017)

mTOR-Related Cell-Clearing Systems in Epileptic Seizures, an Update
por: Limanaqi, Fiona, et al.
Publicado: (2020)

Detailing the ultrastructure’s increase of prion protein in pancreatic adenocarcinoma
por: Bianchini, Matteo, et al.
Publicado: (2021)

Autophagy Activation Associates with Suppression of Prion Protein and Improved Mitochondrial Status in Glioblastoma Cells
por: Lenzi, Paola, et al.
Publicado: (2023)

Stoichiometric Analysis of Shifting in Subcellular Compartmentalization of HSP70 within Ischemic Penumbra
por: Mastroiacovo, Federica, et al.
Publicado: (2021)

The Baseline Structure of the Enteric Nervous System and Its Role in Parkinson’s Disease
por: Natale, Gianfranco, et al.
Publicado: (2021)

Systematic Morphometry of Catecholamine Nuclei in the Brainstem
por: Bucci, Domenico, et al.
Publicado: (2017)

Interdependency Between Autophagy and Synaptic Vesicle Trafficking: Implications for Dopamine Release
por: Limanaqi, Fiona, et al.
Publicado: (2018)

Egas Moniz: 90 Years (1927–2017) from Cerebral Angiography
por: Artico, Marco, et al.
Publicado: (2017)

Vacuolar Protein Sorting Genes in Parkinson's Disease: A Re-appraisal of Mutations Detection Rate and Neurobiology of Disease
por: Gambardella, Stefano, et al.
Publicado: (2016)

Alterations of Mitochondrial Structure in Methamphetamine Toxicity
por: Lenzi, Paola, et al.
Publicado: (2022)

Neuroprotective Effects of Curcumin in Methamphetamine-Induced Toxicity
por: Ryskalin, Larisa, et al.
Publicado: (2021)

Bacopa Protects against Neurotoxicity Induced by MPP(+) and Methamphetamine
por: Ferrucci, Michela, et al.
Publicado: (2022)

Autophagy-Based Hypothesis on the Role of Brain Catecholamine Response During Stress
por: Limanaqi, Fiona, et al.
Publicado: (2020)

Autophagy Activation Promoted by Pulses of Light and Phytochemicals Counteracting Oxidative Stress during Age-Related Macular Degeneration
por: Pinelli, Roberto, et al.
Publicado: (2023)

Rapamycin Ameliorates Defects in Mitochondrial Fission and Mitophagy in Glioblastoma Cells
por: Lenzi, Paola, et al.
Publicado: (2021)

Compartment-dependent mitochondrial alterations in experimental ALS, the effects of mitophagy and mitochondriogenesis
por: Natale, Gianfranco, et al.
Publicado: (2015)

Corticosterone Upregulates Gene and Protein Expression of Catecholamine Markers in Organotypic Brainstem Cultures
por: Busceti, Carla L., et al.
Publicado: (2019)

Epigenetic Effects Induced by Methamphetamine and Methamphetamine-Dependent Oxidative Stress
por: Limanaqi, Fiona, et al.
Publicado: (2018)

A Sentinel in the Crosstalk Between the Nervous and Immune System: The (Immuno)-Proteasome
por: Limanaqi, Fiona, et al.
Publicado: (2019)

Cell Clearing Systems as Targets of Polyphenols in Viral Infections: Potential Implications for COVID-19 Pathogenesis
por: Limanaqi, Fiona, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_i9b77bejjblu6cu7tvm7n9e33c