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Gastrointestinal Stromal Tumors (GISTs): Novel Therapeutic Strategies with Immunotherapy and Small Molecules

Gastrointestinal stromal tumors (GISTs) are the most common types of malignant mesenchymal tumors in the gastrointestinal tract, with an estimated incidence of 1.5/100.000 per year and 1–2% of gastrointestinal neoplasms. About 75–80% of patients have mutations in the KIT gene in exons 9, 11, 13, 14,...

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Detalles Bibliográficos
Autores principales: Vallilas, Christos, Sarantis, Panagiotis, Kyriazoglou, Anastasios, Koustas, Evangelos, Theocharis, Stamatios, Papavassiliou, Athanasios G., Karamouzis, Michalis V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825300/
https://www.ncbi.nlm.nih.gov/pubmed/33419029
http://dx.doi.org/10.3390/ijms22020493