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Gastrointestinal Stromal Tumors (GISTs): Novel Therapeutic Strategies with Immunotherapy and Small Molecules
Gastrointestinal stromal tumors (GISTs) are the most common types of malignant mesenchymal tumors in the gastrointestinal tract, with an estimated incidence of 1.5/100.000 per year and 1–2% of gastrointestinal neoplasms. About 75–80% of patients have mutations in the KIT gene in exons 9, 11, 13, 14,...
Autores principales: | Vallilas, Christos, Sarantis, Panagiotis, Kyriazoglou, Anastasios, Koustas, Evangelos, Theocharis, Stamatios, Papavassiliou, Athanasios G., Karamouzis, Michalis V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825300/ https://www.ncbi.nlm.nih.gov/pubmed/33419029 http://dx.doi.org/10.3390/ijms22020493 |
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