Peptide Blocking CTLA-4 and B7-1 Interaction

Discovery of the B7 family immune checkpoints such as CTLA-4 (CD152), PD-1 (CD279), as well as their ligands B7-1 (CD80), B7-2 (CD86), B7-H1 (PD-L1, CD274), and B7-DC (PD-L2, CD273), has opened new possibilities for cancer immunotherapy using monoclonal antibodies (mAb). The blockade of inhibitory r...

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Detalles Bibliográficos
Autores principales: Podlesnykh, Stepan V., Abramova, Kristina E., Gordeeva, Anastasia, Khlebnikov, Andrei I., Chapoval, Andrei I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825301/
https://www.ncbi.nlm.nih.gov/pubmed/33419027
http://dx.doi.org/10.3390/molecules26020253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825301/
https://www.ncbi.nlm.nih.gov/pubmed/33419027
http://dx.doi.org/10.3390/molecules26020253

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