Cargando…

Ectopic Expression of Ankrd2 Affects Proliferation, Motility and Clonogenic Potential of Human Osteosarcoma Cells

SIMPLE SUMMARY: Osteosarcoma is a rare malignancy of bone, primarily affecting children and young adults. The main objective of this study was to identify novel therapeutic targets to fight the progression of this insidious disease. To this aim, the role of Ankrd2, a stress- and mechano- sensor prot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Piazzi, Manuela, Kojic, Snezana, Capanni, Cristina, Stamenkovic, Nemanja, Bavelloni, Alberto, Marin, Oriano, Lattanzi, Giovanna, Blalock, William, Cenni, Vittoria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7825408/ https://www.ncbi.nlm.nih.gov/pubmed/33419058 http://dx.doi.org/10.3390/cancers13020174

Ejemplares similares

Ankrd2 in Mechanotransduction and Oxidative Stress Response in Skeletal Muscle: New Cues for the Pathogenesis of Muscular Laminopathies
por: Cenni, Vittoria, et al.
Publicado: (2019)

Revisiting the Role of GSK3, A Modulator of Innate Immunity, in Idiopathic Inclusion Body Myositis
por: Piazzi, Manuela, et al.
Publicado: (2021)

Ankrd2/ARPP is a novel Akt2 specific substrate and regulates myogenic differentiation upon cellular exposure to H(2)O(2)
por: Cenni, Vittoria, et al.
Publicado: (2011)

Combined Treatment with PI3K Inhibitors BYL-719 and CAL-101 Is a Promising Antiproliferative Strategy in Human Rhabdomyosarcoma Cells
por: Piazzi, Manuela, et al.
Publicado: (2022)

Emerin Phosphorylation during the Early Phase of the Oxidative Stress Response Influences Emerin–BAF Interaction and BAF Nuclear Localization
por: Cenni, Vittoria, et al.
Publicado: (2020)

Glycogen synthase kinase (GSK)-3 and the double-strand RNA-dependent kinase, PKR: When two kinases for the common good turn bad()
por: Piazzi, Manuela, et al.
Publicado: (2020)

PCAF Involvement in Lamin A/C-HDAC2 Interplay during the Early Phase of Muscle Differentiation
por: Santi, Spartaco, et al.
Publicado: (2020)

Signal Transduction in Ribosome Biogenesis: A Recipe to Avoid Disaster
por: Piazzi, Manuela, et al.
Publicado: (2019)

Alternative Splicing, RNA Editing, and the Current Limits of Next Generation Sequencing
por: Piazzi, Manuela, et al.
Publicado: (2023)

Barrier-to-Autointegration Factor (BAF) involvement in prelamin A-related chromatin organization changes
por: Loi, Manuela, et al.
Publicado: (2015)

Diverse lamin-dependent mechanisms interact to control chromatin dynamics: Focus on laminopathies
por: Camozzi, Daria, et al.
Publicado: (2014)

Multi-Tasking Role of the Mechanosensing Protein Ankrd2 in the Signaling Network of Striated Muscle
por: Belgrano, Anna, et al.
Publicado: (2011)

Potential therapeutic effects of the MTOR inhibitors for preventing ageing and progeria‐related disorders
por: Evangelisti, Camilla, et al.
Publicado: (2016)

ZASP Interacts with the Mechanosensing Protein Ankrd2 and p53 in the Signalling Network of Striated Muscle
por: Martinelli, Valentina C., et al.
Publicado: (2014)

Familial partial lipodystrophy, mandibuloacral dysplasia and restrictive dermopathy feature barrier-to-autointegration factor (BAF) nuclear redistribution
por: Capanni, Cristina, et al.
Publicado: (2012)

The Cytotoxic Effect of Curcumin in Rhabdomyosarcoma Is Associated with the Modulation of AMPK, AKT/mTOR, STAT, and p53 Signaling
por: Salucci, Sara, et al.
Publicado: (2023)

Altered chromatin organization and SUN2 localization in mandibuloacral dysplasia are rescued by drug treatment
por: Camozzi, Daria, et al.
Publicado: (2012)

Ankrd2 is a modulator of NF-κB-mediated inflammatory responses during muscle differentiation
por: Bean, C, et al.
Publicado: (2014)

Ankrd31 in Sperm and Epididymal Integrity
por: Manfrevola, Francesco, et al.
Publicado: (2021)

Clonogenic Assay of Gastric Adenocarcinoma Stem Cells: Clonogenic Assay, Stomach Cancer
por: Kim, Hoon Kyo, et al.
Publicado: (1987)

In triple negative breast tumor cells, PLC-β2 promotes the conversion of CD133(high) to CD133(low) phenotype and reduces the CD133-related invasiveness
por: Brugnoli, Federica, et al.
Publicado: (2013)

ANKRD22 is involved in the progression of prostate cancer
por: Qiu, Yiqing, et al.
Publicado: (2019)

Interactome of the Autoimmune Risk Protein ANKRD55
por: Ugidos, Nerea, et al.
Publicado: (2019)

The Cutting Edge: The Role of mTOR Signaling in Laminopathies
por: Chiarini, Francesca, et al.
Publicado: (2019)

Rapamycin treatment of Mandibuloacral Dysplasia cells rescues localization of chromatin-associated proteins and cell cycle dynamics
por: Cenni, Vittoria, et al.
Publicado: (2014)

An artefact in clonogenic assays of bleomycin cytotoxicity.
por: Twentyman, P. R.
Publicado: (1977)

hnRNPL-activated circANKRD42 back-splicing and circANKRD42-mediated crosstalk of mechanical stiffness and biochemical signal in lung fibrosis
por: Xu, Pan, et al.
Publicado: (2022)

A rapid standardized quantitative microfluidic system approach for evaluating human tear proteins
por: Versura, Piera, et al.
Publicado: (2012)

Prexasertib (LY2606368) reduces clonogenic survival by inducing apoptosis in primary patient‐derived osteosarcoma cells and synergizes with cisplatin and talazoparib
por: Heidler, Christopher L., et al.
Publicado: (2019)

Detection of mesenchymal stem cells senescence by prelamin A accumulation at the nuclear level
por: Bellotti, Chiara, et al.
Publicado: (2016)

Further delineation of the KBG syndrome caused by ANKRD11 aberrations
por: Ockeloen, Charlotte W, et al.
Publicado: (2015)

Control of nuclear-cytoplasmic shuttling of Ankrd54 by PKCδ
por: Samuels, Amy L, et al.
Publicado: (2017)

ANKRD24 organizes TRIOBP to reinforce stereocilia insertion points
por: Krey, Jocelyn F., et al.
Publicado: (2022)

Fluorescence discrimination between diploid cells on their RNA content: a possible distinction between clonogenic and non-clonogenic cells.
por: Watson, J. V., et al.
Publicado: (1977)

Interleukin‐6 neutralization ameliorates symptoms in prematurely aged mice
por: Squarzoni, Stefano, et al.
Publicado: (2021)

Clonogenicity: Holoclones and Meroclones Contain Stem Cells
por: Beaver, Charlotte M., et al.
Publicado: (2014)

Miniaturization of the Clonogenic Assay Using Confluence Measurement
por: Mayr, Christian, et al.
Publicado: (2018)

Spatiotemporal regulation of clonogenicity in colorectal cancer xenografts
por: van der Heijden, Maartje, et al.
Publicado: (2019)

Induction of Ankrd1 in Dilated Cardiomyopathy Correlates with the Heart Failure Progression
por: Bogomolovas, Julius, et al.
Publicado: (2015)

Further delineation of the KBG syndrome phenotype caused by ANKRD11 aberrations
por: Ockeloen, Charlotte W, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_rr3f4buks6ir1js8fibg0f5go9